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- Title
Targeting CD47 as a Novel Immunotherapy for Breast Cancer.
- Authors
Can Chen; Runlu Wang; Xi Chen; Yulong Hou; Jingting Jiang
- Abstract
Nowadays, breast cancer has become the most common cancer worldwide with a high mortality rate. Immune checkpoint blockade holds great promise in tumor-targeted therapy, and CD47 blockade as one immune therapy is undergoing various preclinical studies and clinical trials to demonstrate its safety and efficacy in breast cancer. In this review, we summarized different therapeutic mechanisms targeting CD47 and its prognostic role and therapeutic value in breast cancer.
- Subjects
CD47 antigen; BREAST cancer; IMMUNE checkpoint proteins; IMMUNOTHERAPY; IMMUNE checkpoint inhibitors
- Publication
Frontiers in Oncology, 2022, Vol 12, p1
- ISSN
2234-943X
- Publication type
Article
- DOI
10.3389/fonc.2022.924740