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In Vitro Model of Fully Differentiated Human Nasal Epithelial Cells Infected With Rhinovirus Reveals Epithelium-Initiated Immune Responses.
Published in:
2018
By:
- Kai Sen Tan;
- Hsiao Hui Ong;
- Yan Yan;
- Jing Liu;
- Chunwei Li;
- Yew Kwang Ong;
- Kim Thye Thong;
- Hyung Won Choi;
- De-Yun Wang;
- Vincent T. Chow;
- Tan, Kai Sen;
- Ong, Hsiao Hui;
- Yan, Yan;
- Liu, Jing;
- Li, Chunwei;
- Ong, Yew Kwang;
- Thong, Kim Thye;
- Choi, Hyung Won;
- Wang, De-Yun;
- Chow, Vincent T
Publication type:
journal article
Evaluation of In Vitro and In Vivo Antiviral Activities of Vitamin D for SARS-CoV-2 and Variants.
Published in:
Pharmaceutics, 2023, v. 15, n. 3, p. 925, doi. 10.3390/pharmaceutics15030925
By:
- Mok, Chee-Keng;
- Ng, Yan Ling;
- Ahidjo, Bintou Ahmadou;
- Aw, Zhen Qin;
- Chen, Huixin;
- Wong, Yi Hao;
- Lee, Regina Ching Hua;
- Loe, Marcus Wing Choy;
- Liu, Jing;
- Tan, Kai Sen;
- Kaur, Parveen;
- Wang, De Yun;
- Hao, Erwei;
- Hou, Xiaotao;
- Tan, Yong Wah;
- Deng, Jiagang;
- Chu, Justin Jang Hann
Publication type:
Article
Mucus composition abnormalities in sinonasal mucosa of chronic rhinosinusitis with and without nasal polyps.
Published in:
Inflammation, 2021, v. 44, n. 5, p. 1937, doi. 10.1007/s10753-021-01471-6
By:
- Tu, Yanyi;
- Liu, Jing;
- Li, Tao;
- Zhou, Xiangmin;
- Tan, Kai Sen;
- Ong, Hsiao Hui;
- Sun, Kaiyue;
- Ouyang, Yi;
- Liang, Xu;
- Ong, Yew Kwang;
- Thong, Mark;
- Shi, Li;
- Wang, De-Yun
Publication type:
Article
Motile Ciliary Disorders in Chronic Airway Inflammatory Diseases: Critical Target for Interventions.
Published in:
Current Allergy & Asthma Reports, 2018, v. 18, n. 9, p. 1, doi. 10.1007/s11882-018-0802-x
By:
- Guan, Wei-jie;
- Peng, Yang;
- Zi, Xiao-xue;
- Tan, Kai Sen;
- He, Ting-ting;
- Zhong, Nan-shan;
- Wang, De Yun
Publication type:
Article
Tetraspanins: Host Factors in Viral Infections.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11609, doi. 10.3390/ijms222111609
By:
- New, ChihSheng;
- Lee, Zhao-Yong;
- Tan, Kai Sen;
- Wong, Amanda Huee-Ping;
- Wang, De Yun;
- Tran, Thai
Publication type:
Article
Differential effects of microRNAs miR‐21, miR‐99 and miR‐145 on lung regeneration and inflammation during recovery from influenza pneumonia.
Published in:
Journal of Medical Virology, 2023, v. 95, n. 12, p. 1, doi. 10.1002/jmv.29286
By:
- Ong, Joe Wee Jian;
- Tan, Kai Sen;
- Lee, Joseph Jing Xian;
- Seet, Ju Ee;
- Choi, Hyung Won;
- Ler, Siok Ghee;
- Gunaratne, Jayantha;
- Narasaraju, Teluguakula;
- Sham, Lok‐To;
- Patzel, Volker;
- Chow, Vincent T.
Publication type:
Article
Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection.
Published in:
2019
By:
- Chen, Zhuang Gui;
- Wang, Zhao Ni;
- Yan, Yan;
- Liu, Jing;
- He, Ting Ting;
- Thong, Kim Thye;
- Ong, Yew Kwang;
- Chow, Vincent T. K.;
- Tan, Kai Sen;
- Wang, De Yun
Publication type:
journal article
Uncovering Novel Viral Innate Immune Evasion Strategies: What Has SARS-CoV-2 Taught Us?
Published in:
Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.844447
By:
- Tay, Douglas Jie Wen;
- Lew, Zhe Zhang Ryan;
- Chu, Justin Jang Hann;
- Tan, Kai Sen
Publication type:
Article
A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02514
By:
- Luukkainen, Annika;
- Puan, Kia Joo;
- Yusof, Nurhashikin;
- Lee, Bernett;
- Tan, Kai Sen;
- Liu, Jing;
- Yan, Yan;
- Toppila-Salmi, Sanna;
- Renkonen, Risto;
- Chow, Vincent T.;
- Rotzschke, Olaf;
- Wang, De Yun
Publication type:
Article
Aberrant localization of FOXJ1 correlates with the disease severity and comorbidities in patients with nasal polyps.
Published in:
Allergy, Asthma & Clinical Immunology, 2018, v. 14, n. 1, p. N.PAG, doi. 10.1186/s13223-018-0296-z
By:
- Peng, Yang;
- Guan, Wei-jie;
- Tan, Kai Sen;
- Zhu, Zhenchao;
- Chen, Zhuo;
- Hong, Haiyu;
- Wang, Zhaoni;
- Tian, Tengfei;
- Zi, Xiaoxue;
- Ong, Yew Kwang;
- Thong, Mark;
- Shi, Li;
- Yang, Qintai;
- Qiu, Qianhui;
- Wang, De-Yun
Publication type:
Article
Distribution and Determinants of Dermatophagoides Mites Sensitization ofAllergic Rhinitis and Allergic Asthma in China.
Published in:
International Archives of Allergy & Immunology, 2019, v. 180, n. 1, p. 17, doi. 10.1159/000499409
By:
- Chen, Zhuang-Gui;
- Li, Ya-Ting;
- Wang, Wei-Hao;
- Tan, Kai Sen;
- Zheng, Rui;
- Yang, Li-Fen;
- Guan, Wei-Jie;
- Hong, Hai-Yu;
- Yang, Qin-Tai
Publication type:
Article
Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa.
Published in:
International Archives of Allergy & Immunology, 2018, v. 176, n. 2, p. 115, doi. 10.1159/000488014
By:
- Peng, Yang;
- Chen, Zhuo;
- Guan, Wei-Jie;
- Zhu, Zhenchao;
- Tan, Kai Sen;
- Hong, Haiyu;
- Zi, Xiaoxue;
- Zeng, Jie;
- Li, Yixuan;
- Ong, Yew Kwang;
- Thong, Mark;
- Shi, Li;
- Yang, Qintai;
- Qiu, Qianhui ;
- Wang, De-Yun
Publication type:
Article
Sinus computed tomography predicts clinical response to corticosteroids in chronic rhinosinusitis with nasal polyps.
Published in:
Clinical & Translational Allergy, 2018, v. 8, n. 1, p. N.PAG, doi. 10.1186/s13601-018-0211-1
By:
- Hong, Haiyu;
- Wang, Dan;
- Tan, Kai Sen;
- Zheng, Rui;
- Chen, Fenghong;
- Gao, Wenxiang;
- He, Haixin;
- Shi, Jianbo;
- Fan, Yunping;
- Yang, Qintai;
- Sun, Yueqi
Publication type:
Article
Overexpression of Neutrophil MMP-9 and HIF-1α May Contribute to the Finger-Like Projections Formation and Histo-Pathogenesis in Nasal Inverted Papilloma.
Published in:
Journal of Inflammation Research, 2021, v. 14, p. 2979, doi. 10.2147/JIR.S312605
By:
- Li, Tao;
- Tan, Kai Sen;
- Tu, Yan Yi;
- Zhao, Li;
- Liu, Jing;
- Ong, Hsiao Hui;
- Wang, De Yun;
- Shi, Li
Publication type:
Article
Induction of IL-25 Expression in Human Nasal Polyp Epithelium by Influenza Virus Infection is Abated by Interferon-Alpha Pretreatment.
Published in:
Journal of Inflammation Research, 2021, v. 14, p. 2769, doi. 10.2147/JIR.S304320
By:
- Hong, Haiyu;
- Tan, Kai Sen;
- Yan, Yan;
- Chen, Fenghong;
- Ong, Hsiao Hui;
- Oo, Yukei;
- Liu, Jing;
- Ong, Yew Kwang;
- Thong, Mark;
- Sugrue, Richard;
- Chow, Vincent T;
- Wang, De Yun
Publication type:
Article
Absence or mislocalization of DNAH5 is a characteristic marker for motile ciliary abnormality in nasal polyps.
Published in:
2018
By:
- Qiu, Qianhui;
- Peng, Yang;
- Zhu, Zhenchao;
- Chen, Zhuo;
- Zhang, Chi;
- Ong, Hsiao Hui;
- Tan, Kai Sen;
- Hong, Haiyu;
- Yan, Yan;
- Huang, Haoqi;
- Liu, Jing;
- Li, Xianqing;
- Nam, H. N.;
- Dung, N. T. N.;
- Shi, Li;
- Yang, Qintai;
- Bingle, Colin D.;
- Wang, De‐Yun;
- Wang, De-Yun
Publication type:
journal article
Vaping and Respiratory Viruses: The End for ENDS?
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2021, v. 64, n. 1, p. 16, doi. 10.1165/rcmb.2020-0501ED
By:
- Kai Sen Tan;
- De Yun Wang
Publication type:
Article
An Integrated Analysis of Radial Spoke Head and Outer Dynein Arm Protein Defects and Ciliogenesis Abnormality in Nasal Polyps.
Published in:
Frontiers in Genetics, 2019, v. 10, p. 1, doi. 10.3389/fgene.2019.01083
By:
- Zi, Xiao-xue;
- Guan, Wei-jie;
- Peng, Yang;
- Tan, Kai Sen;
- Liu, Jing;
- He, Ting-ting;
- Ong, Yew-kwang;
- Thong, Mark;
- Shi, Li;
- Wang, De-yun
Publication type:
Article
Zero Secondary Transmission from Three Traveling COVID-19 Cases in China: A Case for Social Responsibility from the General Public in Stemming the Chain of Transmission.
Published in:
Risk Management & Healthcare Policy, 2022, v. 15, p. 107, doi. 10.2147/RMHP.S328950
By:
- Su, Rongfei;
- Hu, Yuqi;
- Liao, Zhenpeng;
- Tan, Kai Sen;
- Hong, Haiyu;
- Fan, Yunping
Publication type:
Article
Investigating the efficacy of pamidronate, a chemical inhibitor of farnesyl pyrophosphate synthase, in the inhibition of influenza virus infection in vitro and in vivo.
Published in:
Molecular Medicine Reports, 2014, v. 9, n. 1, p. 51, doi. 10.3892/mmr.2013.1750
By:
- KAI SEN TAN;
- WAI CHIING;
- SEET, JUEE;
- OLFAT, FARZAD;
- ENGELWARD, BEVIN P.;
- CHOW, VINCENT T. K.
Publication type:
Article
Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Respiratory Aerosols Emitted by Patients With Coronavirus Disease 2019 (COVID-19) While Breathing, Talking, and Singing.
Published in:
Clinical Infectious Diseases, 2022, v. 74, n. 10, p. 1722, doi. 10.1093/cid/ciab691
By:
- Coleman, Kristen K;
- Tay, Douglas Jie Wen;
- Tan, Kai Sen;
- Ong, Sean Wei Xiang;
- Than, The Son;
- Koh, Ming Hui;
- Chin, Yi Qing;
- Nasir, Haziq;
- Mak, Tze Minn;
- Chu, Justin Jang Hann;
- Milton, Donald K;
- Chow, Vincent T K;
- Tambyah, Paul Anantharajah;
- Chen, Mark;
- Tham, Kwok Wai
Publication type:
Article
p63<sup>+</sup>Krt5<sup>+</sup> basal cells are increased in the squamous metaplastic epithelium of patients with radiation-induced chronic Rhinosinusitis.
Published in:
2020
By:
- Huang, Hongming;
- Tan, Kai Sen;
- Zhou, Suizi;
- Yuan, Tian;
- Liu, Jing;
- Ong, Hsiao Hui;
- Chen, Qianmin;
- Gao, Junxiao;
- Xu, Minghong;
- Zhu, Zhenchao;
- Qiu, Qianhui;
- Wang, De Yun
Publication type:
journal article
Insights into Early Recovery from Influenza Pneumonia by Spatial and Temporal Quantification of Putative Lung Regenerating Cells and by Lung Proteomics.
Published in:
Cells (2073-4409), 2019, v. 8, n. 9, p. 975, doi. 10.3390/cells8090975
By:
- Ong, Joe Wee Jian;
- Tan, Kai Sen;
- Ler, Siok Ghee;
- Gunaratne, Jayantha;
- Choi, Hyungwon;
- Seet, Ju Ee;
- Chow, Vincent Tak-Kwong
Publication type:
Article
RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications.
Published in:
Cells (2073-4409), 2019, v. 8, n. 9, p. 986, doi. 10.3390/cells8090986
By:
- Tan, Kai Sen;
- Andiappan, Anand Kumar;
- Lee, Bernett;
- Yan, Yan;
- Liu, Jing;
- Tang, See Aik;
- Lum, Josephine;
- He, Ting Ting;
- Ong, Yew Kwang;
- Thong, Mark;
- Lim, Hui Fang;
- Choi, Hyung Won;
- Rotzschke, Olaf;
- Chow, Vincent T;
- Wang, De Yun
Publication type:
Article
Transcriptomics of rhinovirus persistence reveals sustained expression of RIG‐I and interferon‐stimulated genes in nasal epithelial cells in vitro.
Published in:
Allergy, 2022, v. 77, n. 9, p. 2778, doi. 10.1111/all.15280
By:
- Ong, Hsiao Hui;
- Andiappan, Anand Kumar;
- Duan, Kaibo;
- Lum, Josephine;
- Liu, Jing;
- Tan, Kai Sen;
- Howland, Shanshan;
- Lee, Bernett;
- Ong, Yew Kwang;
- Thong, Mark;
- Chow, Vincent T.;
- Wang, De‐Yun
Publication type:
Article
Corrigendum: Role of yes‐associated protein in interleukin‐13 induced nasal remodeling of chronic rhinosinusitis with nasal polyps.
Published in:
Allergy, 2022, v. 77, n. 2, p. 713, doi. 10.1111/all.15172
By:
- Yuan, Tian;
- Zheng, Rui;
- Liu, Jing;
- Tan, Kai Sen;
- Huang, Zhi‐qun;
- Zhou, Xiang‐Min;
- Zi, Xiao‐xue;
- Qiu, Hui‐jun;
- Wang, Xin‐yue;
- Wang, Wei‐hao;
- Deng, Hui‐yi;
- Chen, Yu‐bin;
- Kong, Wei‐feng;
- Wu, Qing‐wu;
- Huang, Ying;
- Ong, Hsiao Hui;
- Huang, Xue‐kun;
- Chen, Zhuang‐gui;
- Wang, De‐Yun;
- Yang, Qin‐Tai
Publication type:
Article
Role of yes‐associated protein in interleukin‐13 induced nasal remodeling of chronic rhinosinusitis with nasal polyps.
Published in:
Allergy, 2021, v. 76, n. 2, p. 600, doi. 10.1111/all.14699
By:
- Yuan, Tian;
- Zheng, Rui;
- Liu, Jing;
- Tan, Kai Sen;
- Huang, Zhi‐qun;
- Zhou, Xiang‐Min;
- Zi, Xiao‐xue;
- Qiu, Hui‐jun;
- Wang, Xin‐yue;
- Wang, Wei‐hao;
- Deng, Hui‐yi;
- Chen, Yu‐bin;
- Kong, Wei‐feng;
- Wu, Qing‐wu;
- Huang, Ying;
- Ong, Hsiao Hui;
- Huang, Xue‐kun;
- Chen, Zhuang‐gui;
- Wang, De‐Yun;
- Yang, Qin‐Tai
Publication type:
Article
Hypoxia‐induced factor‐1α induces NLRP3 expression by M1 macrophages in noneosinophilic chronic rhinosinusitis with nasal polyps.
Published in:
Allergy, 2021, v. 76, n. 2, p. 582, doi. 10.1111/all.14571
By:
- Zhong, Bing;
- Du, Jintao;
- Liu, Feng;
- Liu, Yafeng;
- Liu, Shixi;
- Zhang, Jie;
- Lin, Ping;
- Zhou, Jiao;
- Liu, Jing;
- Ong, Hsiao Hui;
- Tan, Kai Sen;
- Wang, Deyun;
- Ba, Luo
Publication type:
Article
Type 2‐low asthma phenotypes by integration of sputum transcriptomics and serum proteomics.
Published in:
Allergy, 2021, v. 76, n. 1, p. 380, doi. 10.1111/all.14573
By:
- Zounemat Kermani, Nazanin;
- Saqi, Mansoor;
- Agapow, Paul;
- Pavlidis, Stelios;
- Kuo, Chihhsi;
- Tan, Kai Sen;
- Mumby, Sharon;
- Sun, Kai;
- Loza, Matthew;
- Baribaud, Frederic;
- Sousa, Ana R.;
- Riley, John;
- Wheelock, Asa M.;
- Wheelock, Craig E.;
- De Meulder, Bertrand;
- Schofield, Jim;
- Sánchez‐Ovando, Stephany;
- Simpson, Jodie Louise;
- Baines, Katherine Joanne;
- Wark, Peter A.
Publication type:
Article
The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status.
Published in:
Military Medical Research, 2020, v. 7, n. 1, p. 1, doi. 10.1186/s40779-020-00240-0
By:
- Guo, Yan-Rong;
- Cao, Qing-Dong;
- Hong, Zhong-Si;
- Tan, Yuan-Yang;
- Chen, Shou-Deng;
- Jin, Hong-Jun;
- Tan, Kai-Sen;
- Wang, De-Yun;
- Yan, Yan
Publication type:
Article
Micro-RNAs in regenerating lungs: an integrative systems biology analysis of murine influenza pneumonia
Published in:
BMC Genomics, 2014, v. 15, n. 1, p. 587, doi. 10.1186/1471-2164-15-587
By:
- Kai Sen Tan;
- Hyungwon Choi;
- Xiaoou Jiang;
- Lu Yin;
- Ju Ee Seet;
- Patzel, Volker;
- Engelward, Bevin P;
- Chow, Vincent T
Publication type:
Article
Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles.
Published in:
PLoS Pathogens, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.ppat.1009130
By:
- Gamage, Akshamal M.;
- Tan, Kai Sen;
- Chan, Wharton O. Y.;
- Liu, Jing;
- Tan, Chee Wah;
- Ong, Yew Kwang;
- Thong, Mark;
- Andiappan, Anand K.;
- Anderson, Danielle E.;
- Wang, De Yun;
- Wang, Lin-Fa
Publication type:
Article
Comparative Transcriptomic and Metagenomic Analyses of Influenza Virus-Infected Nasal Epithelial Cells From Multiple Individuals Reveal Specific Nasal-Initiated Signatures.
Published in:
Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.02685
By:
- Tan, Kai Sen;
- Yan, Yan;
- Koh, Wai Ling Hiromi;
- Li, Liang;
- Choi, Hyungwon;
- Tran, Thai;
- Sugrue, Richard;
- Wang, De Yun;
- Chow, Vincent T.
Publication type:
Article
Decreased hospital charges and postoperative pain in septoplasty by application of enhanced recovery after surgery.
Published in:
2018
By:
- Liao, Zhenpeng;
- Liao, Wei;
- Tan, Kai Sen;
- Sun, Yueqi;
- Peng, Aiqing;
- Zhu, Yingxian;
- He, Haixin;
- Yang, Shuowei;
- Xu, Guangfu;
- Su, Rongfei;
- Yao, Jinyu;
- Fan, Yunping;
- Yang, Qintai;
- Hong, Haiyu
Publication type:
journal article
Microarray Assay Reveals Ciliary Abnormalities of the Allergic Nasal Mucosa.
Published in:
American Journal of Rhinology & Allergy, 2020, v. 34, n. 1, p. 50, doi. 10.1177/1945892419871795
By:
- Peng, Yang;
- Guan, Wei-jie;
- Zhu, Zhen-chao;
- Tan, Kai Sen;
- Chen, Zhuo;
- Hong, Hai-yu;
- Zi, Xiao-xue;
- Andiappan, Anand Kumar;
- Shi, Li;
- Yang, Qin-tai;
- Wang, De-Yun;
- Qiu, Qian-hui
Publication type:
Article

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