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Co-regulation of innate and adaptive immune responses induced by ID93+GLA-SE vaccination in humans.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1441944
By:
- Fiore-Gartland, Andrew;
- Srivastava, Himangi;
- Seese, Aaron;
- Day, Tracey;
- Penn-Nicholson, Adam;
- Luabeya, Angelique Kany Kany;
- Du Plessis, Nelita;
- Loxton, Andre G.;
- Bekker, Linda-Gail;
- Diacon, Andreas;
- Walzl, Gerhard;
- Sagawa, Zachary K.;
- Reed, Steven G.;
- Scriba, Thomas J.;
- Hatheril, Mark;
- Coler, Rhea
Publication type:
Article
In-home TB Testing Using GeneXpert Edge is Acceptable, Feasible, and Improves the Proportion of Symptomatic Household Contacts Tested for TB: A Proof-of-Concept Study.
Published in:
Open Forum Infectious Diseases, 2024, v. 11, n. 6, p. 1, doi. 10.1093/ofid/ofae279
By:
- Medina-Marino, Andrew;
- Bezuidenhout, Dana;
- Bezuidenhout, Charl;
- Facente, Shelley N;
- Fourie, Bernard;
- Shin, Sanghyuk S;
- Penn-Nicholson, Adam;
- Theron, Grant
Publication type:
Article
Host transcriptomic signatures of tuberculosis can predict immune reconstitution inflammatory syndrome in HIV patients.
Published in:
European Journal of Immunology, 2022, v. 52, n. 7, p. 1112, doi. 10.1002/eji.202249815
By:
- Mbandi, Stanley Kimbung;
- Painter, Hannah;
- Penn‐Nicholson, Adam;
- Toefy, Asma;
- Erasmus, Mzwandile;
- Hanekom, Willem A.;
- Scriba, Thomas J.;
- Lai, Rachel P.J.;
- Marais, Suzaan;
- Fletcher, Helen A.;
- Meintjes, Graeme;
- Wilkinson, Robert J.;
- Cotton, Mark F.;
- Pahwa, Savita;
- Cameron, Mark J.;
- Nemes, Elisa
Publication type:
Article
Targeted Gene Expression Profiling of Human Myeloid Cells From Blood and Lung Compartments of Patients With Tuberculosis and Other Lung Diseases.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.839747
By:
- Kotze, Leigh Ann;
- van der Spuy, Gian;
- Leonard, Bryan;
- Penn-Nicholson, Adam;
- Musvosvi, Munyaradzi;
- McAnda, Shirley;
- Malherbe, Stephanus T.;
- Erasmus, Mzwandile;
- Scriba, Thomas;
- Koegelenberg, Coenraad F. N.;
- Allwood, Brian W.;
- Walzl, Gerhard;
- du Plessis, Nelita
Publication type:
Article
Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005817
By:
- Amelio, Patrizia;
- Portevin, Damien;
- Reither, Klaus;
- Mhimbira, Francis;
- Mpina, Maxmillian;
- Tumbo, Anneth;
- Nickel, Beatrice;
- Marti, Hanspeter;
- Knopp, Stefanie;
- Ding, Song;
- Penn-Nicholson, Adam;
- Darboe, Fatoumatta;
- Ohmiti, Khalid;
- Scriba, Thomas J.;
- Pantaleo, Giuseppe;
- Daubenberger, Claudia;
- Perreau, Matthieu
Publication type:
Article
Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis.
Published in:
2021
By:
- Mulenga, Humphrey;
- Musvosvi, Munyaradzi;
- Mendelsohn, Simon C.;
- Penn-Nicholson, Adam;
- Mbandi, Stanley Kimbung;
- Fiore-Gartland, Andrew;
- Tameris, Michele;
- Mabwe, Simbarashe;
- Africa, Hadn;
- Bilek, Nicole;
- Kafaar, Fazlin;
- Khader, Shabaana A.;
- Carstens, Balie;
- Hadley, Katie;
- Hikuam, Chris;
- Erasmus, Mzwandile;
- Jaxa, Lungisa;
- Raphela, Rodney;
- Nombida, Onke;
- Kaskar, Masooda
Publication type:
journal article
Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis.
Published in:
2018
By:
- Suliman, Sara;
- Thompson, Ethan G.;
- Sutherland, Jayne;
- Weiner 3rd, January;
- Ota, Martin O. C.;
- Shankar, Smitha;
- Penn-Nicholson, Adam;
- Thiel, Bonnie;
- Erasmus, Mzwandile;
- Maertzdorf, Jeroen;
- Duffy, Fergal J.;
- Hill, Philip C.;
- Hughes, E. Jane;
- Stanley, Kim;
- Downing, Katrina;
- Fisher, Michelle L.;
- Valvo, Joe;
- Parida, Shreemanta K.;
- van der Spuy, Gian;
- Tromp, Gerard
Publication type:
journal article
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65043-8
By:
- Penn-Nicholson, Adam;
- Mbandi, Stanley Kimbung;
- Thompson, Ethan;
- Mendelsohn, Simon C.;
- Suliman, Sara;
- Chegou, Novel N.;
- Malherbe, Stephanus T.;
- Darboe, Fatoumatta;
- Erasmus, Mzwandile;
- Hanekom, Willem A.;
- Bilek, Nicole;
- Fisher, Michelle;
- Kaufmann, Stefan H. E.;
- Winter, Jill;
- Murphy, Melissa;
- Wood, Robin;
- Morrow, Carl;
- Van Rhijn, Ildiko;
- Moody, Branch;
- Murray, Megan
Publication type:
Article
Potential population level impact on tuberculosis incidence of using an mRNA expression signature correlate-of-risk test to target tuberculosis preventive therapy.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47645-z
By:
- Sumner, Tom;
- Scriba, Thomas J.;
- Penn-Nicholson, Adam;
- Hatherill, Mark;
- White, Richard G.
Publication type:
Article
Biology of CCR5 and Its Role in HIV Infection and Treatment.
Published in:
JAMA: Journal of the American Medical Association, 2006, v. 296, n. 7, p. 815, doi. 10.1001/jama.296.7.815
By:
- Lederman, Michael M.;
- Penn-Nicholson, Adam;
- Cho, Michael;
- Mosier, Donald
Publication type:
Article
Performance of diagnostic and predictive host blood transcriptomic signatures for Tuberculosis disease: A systematic review and meta-analysis.
Published in:
PLoS ONE, 2020, v. 15, n. 8, p. 1, doi. 10.1371/journal.pone.0237574
By:
- Mulenga, Humphrey;
- Zauchenberger, Chambrez-Zita;
- Bunyasi, Erick W.;
- Mbandi, Stanley Kimbung;
- Mendelsohn, Simon C.;
- Kagina, Benjamin;
- Penn-Nicholson, Adam;
- Scriba, Thomas J.;
- Hatherill, Mark
Publication type:
Article
Inflammatory Determinants of Differential Tuberculosis Risk in Pre-Adolescent Children and Young Adults.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.639965
By:
- Baguma, Richard;
- Mbandi, Stanley Kimbung;
- Rodo, Miguel J.;
- Erasmus, Mzwandile;
- Day, Jonathan;
- Makhethe, Lebohang;
- de Kock, Marwou;
- van Rooyen, Michele;
- Stone, Lynnett;
- Bilek, Nicole;
- Steyn, Marcia;
- Africa, Hadn;
- Darboe, Fatoumatta;
- Chegou, Novel N.;
- Tromp, Gerard;
- Walzl, Gerhard;
- Hatherill, Mark;
- Penn-Nicholson, Adam;
- Scriba, Thomas J.
Publication type:
Article
Corrigendum: T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Published in:
Nature Communications, 2016, v. 7, n. 5, p. 11633, doi. 10.1038/ncomms11633
By:
- Fletcher, Helen A.;
- Snowden, Margaret A.;
- Landry, Bernard;
- Rida, Wasima;
- Satti, Iman;
- Harris, Stephanie A.;
- Matsumiya, Magali;
- Tanner, Rachel;
- O'Shea, Matthew K.;
- Dheenadhayalan, Veerabadran;
- Bogardus, Leah;
- Stockdale, Lisa;
- Marsay, Leanne;
- Chomka, Agnieszka;
- Harrington-Kandt, Rachel;
- Manjaly-Thomas, Zita-Rose;
- Naranbhai, Vivek;
- Stylianou, Elena;
- Darboe, Fatoumatta;
- Penn-Nicholson, Adam
Publication type:
Article
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Published in:
Nature Communications, 2016, v. 7, n. 4, p. 11290, doi. 10.1038/ncomms11290
By:
- Fletcher, Helen A.;
- Snowden, Margaret A.;
- Landry, Bernard;
- Rida, Wasima;
- Satti, Iman;
- Harris, Stephanie A.;
- Matsumiya, Magali;
- Tanner, Rachel;
- O'Shea, Matthew K.;
- Dheenadhayalan, Veerabadran;
- Bogardus, Leah;
- Stockdale, Lisa;
- Marsay, Leanne;
- Chomka, Agnieszka;
- Harrington-Kandt, Rachel;
- Manjaly-Thomas, Zita-Rose;
- Naranbhai, Vivek;
- Stylianou, Elena;
- Darboe, Fatoumatta;
- Penn-Nicholson, Adam
Publication type:
Article
Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.
Published in:
PLoS Pathogens, 2017, v. 13, n. 11, p. 1, doi. 10.1371/journal.ppat.1006687
By:
- Scriba, Thomas J.;
- Penn-Nicholson, Adam;
- Shankar, Smitha;
- Hraha, Tom;
- Thompson, Ethan G.;
- Sterling, David;
- Nemes, Elisa;
- Darboe, Fatoumatta;
- Suliman, Sara;
- Amon, Lynn M.;
- Mahomed, Hassan;
- Erasmus, Mzwandile;
- Whatney, Wendy;
- Johnson, John L.;
- Boom, W. Henry;
- Hatherill, Mark;
- Valvo, Joe;
- De Groote, Mary Ann;
- Ochsner, Urs A.;
- Aderem, Alan
Publication type:
Article
Correction: Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.
Published in:
2019
By:
- Penn-Nicholson, Adam;
- Hraha, Thomas;
- Thompson, Ethan G.;
- Sterling, David;
- Mbandi, Stanley Kimbung;
- Wall, Kirsten M.;
- Fisher, Michelle;
- Suliman, Sara;
- Shankar, Smitha;
- Hanekom, Willem A.;
- Janjic, Nebojsa;
- Hatherill, Mark;
- Kaufmann, Stefan H. E.;
- Sutherland, Jayne;
- Walzl, Gerhard;
- De Groote, Mary Ann;
- Ochsner, Urs;
- Zak, Daniel E.;
- Scriba, Thomas J.;
- ACS and GC6–74 cohort study groups
Publication type:
corrected article
Plasma Type I IFN Protein Concentrations in Human Tuberculosis.
Published in:
Frontiers in Cellular & Infection Microbiology, 2019, v. 9, p. 1, doi. 10.3389/fcimb.2019.00296
By:
- Llibre, Alba;
- Bilek, Nicole;
- Bondet, Vincent;
- Darboe, Fatoumatta;
- Mbandi, Stanley Kimbung;
- Penn-Nicholson, Adam;
- Hatherill, Mark;
- Rozenberg, Flore;
- Scriba, Thomas J.;
- Duffy, Darragh
Publication type:
Article
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study.
Published in:
2019
By:
- Penn-Nicholson, Adam;
- Hraha, Thomas;
- Thompson, Ethan G.;
- Sterling, David;
- Mbandi, Stanley Kimbung;
- Wall, Kirsten M.;
- Fisher, Michelle;
- Suliman, Sara;
- Shankar, Smitha;
- Hanekom, Willem A.;
- Janjic, Nebojsa;
- Hatherill, Mark;
- Kaufmann, Stefan H. E.;
- Sutherland, Jayne;
- Walzl, Gerhard;
- De Groote, Mary Ann;
- Ochsner, Urs;
- Zak, Daniel E.;
- Scriba, Thomas J.;
- null, null
Publication type:
journal article
Co-regulation of innate and adaptive immune responses induced by ID93+GLA-SE vaccination in humans.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1441944
By:
- Fiore-Gartland, Andrew;
- Srivastava, Himangi;
- Seese, Aaron;
- Day, Tracey;
- Penn-Nicholson, Adam;
- Kany Luabeya, Angelique Kany;
- Du Plessis, Nelita;
- Loxton, Andre G.;
- Bekker, Linda-Gail;
- Diacon, Andreas;
- Walzl, Gerhard;
- Sagawa, Zachary K.;
- Reed, Steven G.;
- Scriba, Thomas J.;
- Hatherill, Mark;
- Coler, Rhea
Publication type:
Article
A novel blood test for tuberculosis prevention and treatment.
Published in:
SAMJ: South African Medical Journal, 2017, v. 107, n. 1, p. 4, doi. 10.7196/SAMJ.2017.v107i1.12230
By:
- Penn-Nicholson, Adam;
- Scriba, Thomas J.;
- Hatherill, Mark;
- White, Richard G.;
- Sumner, Tom
Publication type:
Article
Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.
Published in:
PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184563
By:
- Baguma, Richard;
- Penn-Nicholson, Adam;
- Smit, Erica;
- Erasmus, Mzwandile;
- Day, Jonathan;
- Makhethe, Lebohang;
- de Kock, Marwou;
- Hughes, E. Jane;
- van Rooyen, Michele;
- Pienaar, Bernadette;
- Stone, Lynnett;
- Hanekom, Willem;
- Brennan, Michael J.;
- Wallis, Robert S.;
- Hatherill, Mark;
- Scriba, Thomas J.
Publication type:
Article

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