We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Stress, mindfulness, and systemic lupus erythematosus: An overview and directions for future research.
- Authors
Molina, Emily; Gould, Neda; Lee, Kristen; Krimins, Rebecca; Hardenbergh, Dylan; Timlin, Homa
- Abstract
Although the pathogenesis of autoimmunity is not fully understood, it is thought to involve genetic, hormonal, immunologic, and environmental factors. Stress has been evaluated as a potential trigger for autoimmunity and disease flares in patients with systemic lupus erythematosus (SLE). The physiologic changes that occur with stress involve numerous catecholamines, hormones, and cytokines that communicate intricately with the immune system. There is some evidence that these systems may be dysregulated in patients with autoimmune disease. Mindfulness-based techniques are practices aimed at mitigating stress response and have been shown to improve quality of life in general population. This review will discuss pathophysiology of chronic stress as it relates to SLE, evidence behind mindfulness-based practices in these patients, and directions for future research.
- Subjects
SYSTEMIC lupus erythematosus; AUTOIMMUNE diseases; MINDFULNESS; IMMUNE system; PSYCHOLOGICAL stress; AUTOIMMUNITY
- Publication
Lupus, 2022, Vol 31, Issue 13, p1549
- ISSN
0961-2033
- Publication type
Article
- DOI
10.1177/09612033221122980