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Translational Research in the Era of Precision Medicine: Where We Are and Where We Will Go.
Published in:
Journal of Personalized Medicine, 2021, v. 11, n. 3, p. 216, doi. 10.3390/jpm11030216
By:
- De Maria Marchiano, Ruggero;
- Di Sante, Gabriele;
- Piro, Geny;
- Carbone, Carmine;
- Tortora, Giampaolo;
- Boldrini, Luca;
- Pietragalla, Antonella;
- Daniele, Gennaro;
- Tredicine, Maria;
- Cesario, Alfredo;
- Valentini, Vincenzo;
- Gallo, Daniela;
- Babini, Gabriele;
- D'Oria, Marika;
- Scambia, Giovanni;
- Gibson, David S.
Publication type:
Article
KRAS-Dependency in Pancreatic Ductal Adenocarcinoma: Mechanisms of Escaping in Resistance to KRAS Inhibitors and Perspectives of Therapy.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9313, doi. 10.3390/ijms24119313
By:
- Gurreri, Enrico;
- Genovese, Giannicola;
- Perelli, Luigi;
- Agostini, Antonio;
- Piro, Geny;
- Carbone, Carmine;
- Tortora, Giampaolo
Publication type:
Article
Intraductal Pancreatic Mucinous Neoplasms: A Tumor-Biology Based Approach for Risk Stratification.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6386, doi. 10.3390/ijms21176386
By:
- Nasca, Vincenzo;
- Chiaravalli, Marta;
- Piro, Geny;
- Esposito, Annachiara;
- Salvatore, Lisa;
- Tortora, Giampaolo;
- Corbo, Vincenzo;
- Carbone, Carmine
Publication type:
Article
Pancreatic Cancer and Obesity: Molecular Mechanisms of Cell Transformation and Chemoresistance.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3331, doi. 10.3390/ijms19113331
By:
- Cascetta, Priscilla;
- Cavaliere, Alessandro;
- Piro, Geny;
- Torroni, Lorena;
- Santoro, Raffaela;
- Tortora, Giampaolo;
- Melisi, Davide;
- Carbone, Carmine
Publication type:
Article
Angiopoietin-Like Proteins in Angiogenesis, Inflammation and Cancer.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 431, doi. 10.3390/ijms19020431
By:
- Carbone, Carmine;
- Piro, Geny;
- Merz, Valeria;
- Simionato, Francesca;
- Santoro, Raffaela;
- Zecchetto, Camilla;
- Tortora, Giampaolo;
- Melisi, Davide
Publication type:
Article
PTEN Loss as a Predictor of Tumor Heterogeneity and Poor Prognosis in Patients With EGFR-mutant Advanced Non–small-cell Lung Cancer Receiving Tyrosine Kinase Inhibitors.
Published in:
Clinical Lung Cancer, 2021, v. 22, n. 4, p. 351, doi. 10.1016/j.cllc.2020.12.008
By:
- Ferrara, Miriam Grazia;
- Martini, Maurizio;
- D'Argento, Ettore;
- Forcella, Chiara;
- Vita, Emanuele;
- Di Noia, Vincenzo;
- Sperduti, Isabella;
- Bilotta, Mirna;
- Ribelli, Marta;
- Damiano, Paola;
- Cannella, Antonella;
- Stefani, Alessio;
- Pilotto, Sara;
- Carbone, Carmine;
- Piro, Geny;
- Milella, Michele;
- Tortora, Giampaolo;
- Bria, Emilio
Publication type:
Article
Leptin-mediated meta-inflammation may provide survival benefit in patients receiving maintenance immunotherapy for extensive-stage small cell lung cancer (ES-SCLC).
Published in:
Cancer Immunology, Immunotherapy, 2023, v. 72, n. 11, p. 3803, doi. 10.1007/s00262-023-03533-0
By:
- Vita, Emanuele;
- Stefani, Alessio;
- Piro, Geny;
- Mastrantoni, Luca;
- Cintoni, Marco;
- Cicchetti, Giuseppe;
- Sparagna, Ileana;
- Monaca, Federico;
- Horn, Guido;
- Russo, Jacopo;
- Barone, Diletta;
- Di Salvatore, Mariantonietta;
- Trisolini, Rocco;
- Lococo, Filippo;
- Mazzarella, Ciro;
- Cancellieri, Alessandra;
- Carbone, Carmine;
- Larici, Anna Rita;
- Mele, Maria Cristina;
- Pilotto, Sara
Publication type:
Article
Tissue transglutaminase (TG2) is involved in the resistance of cancer cells to the histone deacetylase (HDAC) inhibitor vorinostat.
Published in:
Amino Acids, 2017, v. 49, n. 3, p. 517, doi. 10.1007/s00726-016-2338-5
By:
- Carbone, Carmine;
- Di Gennaro, Elena;
- Piro, Geny;
- Milone, Maria;
- Pucci, Biagio;
- Caraglia, Michele;
- Budillon, Alfredo
Publication type:
Article
Emerging multisystem biomarkers in hereditary transthyretin amyloidosis: a pilot study.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-69123-x
By:
- Luigetti, Marco;
- Vitali, Francesca;
- Romano, Angela;
- Sciarrone, Maria Ausilia;
- Guglielmino, Valeria;
- Ardito, Michelangelo;
- Sabino, Andrea;
- Servidei, Serenella;
- Piro, Geny;
- Carbone, Carmine;
- Graziani, Francesca;
- Lillo, Rosa;
- Ferraro, Pietro Manuel;
- Primiano, Guido
Publication type:
Article
Serum Inflammatory Profile in Hereditary Transthyretin Amyloidosis: Mechanisms and Possible Therapeutic Implications.
Published in:
Brain Sciences (2076-3425), 2022, v. 12, n. 12, p. 1708, doi. 10.3390/brainsci12121708
By:
- Luigetti, Marco;
- Romano, Angela;
- Guglielmino, Valeria;
- Sciarrone, Maria Ausilia;
- Vitali, Francesca;
- Carbone, Carmine;
- Piro, Geny;
- Sabino, Andrea;
- De Stefano, Nicola;
- Plantone, Domenico;
- Primiano, Guido
Publication type:
Article
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07654-4
By:
- Fiore, Alessandra;
- Ugel, Stefano;
- De Sanctis, Francesco;
- Sandri, Sara;
- Fracasso, Giulio;
- Trovato, Rosalinda;
- Sartoris, Silvia;
- Solito, Samantha;
- Mandruzzato, Susanna;
- Vascotto, Fulvia;
- Hippen, Keli L.;
- Mondanelli, Giada;
- Grohmann, Ursula;
- Piro, Geny;
- Carbone, Carmine;
- Melisi, Davide;
- Lawlor, Rita T.;
- Scarpa, Aldo;
- Lamolinara, Alessia;
- Iezzi, Manuela
Publication type:
Article
The Role of the Complement in Clear Cell Renal Carcinoma (ccRCC)—What Future Prospects Are There for Its Use in Clinical Practice?
Published in:
Cancers, 2024, v. 16, n. 3, p. 490, doi. 10.3390/cancers16030490
By:
- Panebianco, Martina;
- Ciccarese, Chiara;
- Strusi, Alessandro;
- Beccia, Viria;
- Carbone, Carmine;
- Agostini, Antonio;
- Piro, Geny;
- Tortora, Giampaolo;
- Iacovelli, Roberto
Publication type:
Article
Revising PTEN in the Era of Immunotherapy: New Perspectives for an Old Story.
Published in:
Cancers, 2019, v. 11, n. 10, p. 1525, doi. 10.3390/cancers11101525
By:
- Piro, Geny;
- Carbone, Carmine;
- Carbognin, Luisa;
- Pilotto, Sara;
- Ciccarese, Chiara;
- Iacovelli, Roberto;
- Milella, Michele;
- Bria, Emilio;
- Tortora, Giampaolo
Publication type:
Article
PTEN in Lung Cancer: Dealing with the Problem, Building on New Knowledge and Turning the Game Around.
Published in:
Cancers, 2019, v. 11, n. 8, p. 1141, doi. 10.3390/cancers11081141
By:
- Gkountakos, Anastasios;
- Sartori, Giulia;
- Falcone, Italia;
- Piro, Geny;
- Ciuffreda, Ludovica;
- Carbone, Carmine;
- Tortora, Giampaolo;
- Scarpa, Aldo;
- Bria, Emilio;
- Milella, Michele;
- Rosell, Rafael;
- Corbo, Vincenzo;
- Pilotto, Sara
Publication type:
Article
The Renaissance of KRAS Targeting in Advanced Non-Small-Cell Lung Cancer: New Opportunities Following Old Failures.
Published in:
Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.792385
By:
- Ferrara, Miriam Grazia;
- Stefani, Alessio;
- Pilotto, Sara;
- Carbone, Carmine;
- Vita, Emanuele;
- Di Salvatore, Mariantonietta;
- D'Argento, Ettore;
- Sparagna, Ileana;
- Monaca, Federico;
- Valente, Giustina;
- Vitale, Antonio;
- Piro, Geny;
- Belluomini, Lorenzo;
- Milella, Michele;
- Tortora, Giampaolo;
- Bria, Emilio
Publication type:
Article
Lung and Gut Microbiota as Potential Hidden Driver of Immunotherapy Efficacy in Lung Cancer.
Published in:
Mediators of Inflammation, 2019, p. 1, doi. 10.1155/2019/7652014
By:
- Carbone, Carmine;
- Piro, Geny;
- Di Noia, Vincenzo;
- D'Argento, Ettore;
- Vita, Emanuele;
- Ferrara, Miriam Grazia;
- Pilotto, Sara;
- Milella, Michele;
- Cammarota, Giovanni;
- Gasbarrini, Antonio;
- Tortora, Giampaolo;
- Bria, Emilio
Publication type:
Article
Talniflumate abrogates mucin immune suppressive barrier improving efficacy of gemcitabine and nab-paclitaxel treatment in pancreatic cancer.
Published in:
Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04733-z
By:
- Agostini, Antonio;
- Guerriero, Ilaria;
- Piro, Geny;
- Quero, Giuseppe;
- Roberto, Luca;
- Esposito, Annachiara;
- Caggiano, Alessia;
- Priori, Lorenzo;
- Scaglione, Giulia;
- De Sanctis, Francesco;
- Sistigu, Antonella;
- Musella, Martina;
- Larghi, Alberto;
- Rizzatti, Gianenrico;
- Lucchetti, Donatella;
- Alfieri, Sergio;
- Sgambato, Alessandro;
- Bria, Emilio;
- Bizzozero, Laura;
- Arena, Sabrina
Publication type:
Article
Molecular alterations in basal cell carcinoma subtypes.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-92592-3
By:
- Di Nardo, Lucia;
- Pellegrini, Cristina;
- Di Stefani, Alessandro;
- Ricci, Francesco;
- Fossati, Barbara;
- Del Regno, Laura;
- Carbone, Carmine;
- Piro, Geny;
- Corbo, Vincenzo;
- Delfino, Pietro;
- De Summa, Simona;
- Maturo, Maria Giovanna;
- Rocco, Tea;
- Tortora, Giampaolo;
- Fargnoli, Maria Concetta;
- Peris, Ketty
Publication type:
Article
Inflammatory profile in mitochondrial diseases: A cohort study.
Published in:
European Journal of Neurology, 2023, v. 30, n. 10, p. 3409, doi. 10.1111/ene.15962
By:
- Primiano, Guido;
- Plantone, Domenico;
- Piro, Geny;
- Carbone, Carmine;
- Sabino, Andrea;
- Sancricca, Cristina;
- Di Nottia, Michela;
- Carrozzo, Rosalba;
- Servidei, Serenella
Publication type:
Article
CXCR1/2 dual-inhibitor ladarixin reduces tumour burden and promotes immunotherapy response in pancreatic cancer.
Published in:
2023
By:
- Piro, Geny;
- Carbone, Carmine;
- Agostini, Antonio;
- Esposito, Annachiara;
- De Pizzol, Maria;
- Novelli, Rubina;
- Allegretti, Marcello;
- Aramini, Andrea;
- Caggiano, Alessia;
- Granitto, Alessia;
- De Sanctis, Francesco;
- Ugel, Stefano;
- Corbo, Vincenzo;
- Martini, Maurizio;
- Lawlor, Rita Teresa;
- Scarpa, Aldo;
- Tortora, Giampaolo
Publication type:
journal article
HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT.
Published in:
Journal of Cellular Physiology, 2011, v. 226, n. 9, p. 2378, doi. 10.1002/jcp.22574
By:
- Bruzzese, Francesca;
- Leone, Alessandra;
- Rocco, Monia;
- Carbone, Carmine;
- Piro, Geny;
- Caraglia, Michele;
- Di Gennaro, Elena;
- Budillon, Alfredo
Publication type:
Article
Immunogenic Cell Death: An Emerging Target in Gastrointestinal Cancers.
Published in:
Cells (2073-4409), 2022, v. 11, n. 19, p. 3033, doi. 10.3390/cells11193033
By:
- Chiaravalli, Marta;
- Spring, Alexia;
- Agostini, Antonio;
- Piro, Geny;
- Carbone, Carmine;
- Tortora, Giampaolo
Publication type:
Article
Unweaving the mitotic spindle: A focus on Aurora kinase inhibitors in lung cancer.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.1026020
By:
- Stefani, Alessio;
- Piro, Geny;
- Schietroma, Francesco;
- Strusi, Alessandro;
- Vita, Emanuele;
- Fiorani, Simone;
- Barone, Diletta;
- Monaca, Federico;
- Sparagna, Ileana;
- Valente, Giustina;
- Ferrara, Miriam Grazia;
- D'Argento, Ettore;
- Di Salvatore, Mariantonietta;
- Carbone, Carmine;
- Tortora, Giampaolo;
- Bria, Emilio
Publication type:
Article
Prognostic role of circulating cytokines and inflammation indexes for avelumab maintenance in metastatic urothelial carcinoma.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1401214
By:
- Maiorano, Brigida Anna;
- Schinzari, Giovanni;
- Carbone, Carmine;
- Piro, Geny;
- Rossi, Ernesto;
- Di Maio, Massimo;
- Di Giacomo, Annamaria;
- Maiello, Evaristo
Publication type:
Article
CSF CXCL13 and Chitinase 3-like-1 Levels Predict Disease Course in Relapsing Multiple Sclerosis.
Published in:
Molecular Neurobiology, 2023, v. 60, n. 1, p. 36, doi. 10.1007/s12035-022-03060-6
By:
- Lucchini, Matteo;
- De Arcangelis, Valeria;
- Piro, Geny;
- Nociti, Viviana;
- Bianco, Assunta;
- De Fino, Chiara;
- Di Sante, Gabriele;
- Ria, Francesco;
- Calabresi, Paolo;
- Mirabella, Massimiliano
Publication type:
Article
Gastrointestinal Cancer Patient Nutritional Management: From Specific Needs to Novel Epigenetic Dietary Approaches.
Published in:
Nutrients, 2022, v. 14, n. 8, p. N.PAG, doi. 10.3390/nu14081542
By:
- Cencioni, Chiara;
- Trestini, Ilaria;
- Piro, Geny;
- Bria, Emilio;
- Tortora, Giampaolo;
- Carbone, Carmine;
- Spallotta, Francesco
Publication type:
Article
Systemic profile of immune factors in an elderly Italian population affected by chronic strongyloidiasis.
Published in:
Parasites & Vectors, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13071-020-04391-w
By:
- Tiberti, Natalia;
- Buonfrate, Dora;
- Carbone, Carmine;
- Piro, Geny;
- Bisoffi, Zeno;
- Piubelli, Chiara
Publication type:
Article

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