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- Title
Antibacterial Chitosan of Milkfish Scales (Chanos chanos) on Bacteria Prophyromonas gingivalis & Agregatibacter actinomycetemcomitans.
- Authors
Achmad, Harun; Djais, Arni Irawaty; Jannah, Miftahul; Carmelita, Austin Bertilova; Uinarni, Herlina; Arifin, Evi Mustikawati; Huldani; Putra, Aminuddin Prahatama
- Abstract
This research was conducted to appear the effectiveness of milkfish scales chitosan gel (Chanos Chanos) against bacterial inhibition of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis which are pathogenic bacteria that cause periodontitis. This research was conducted with five treatments with five repetitions, the five treatments, namely: Positive control (metronidazole), negative control (aquadest), chitosan gel in milkfish scales concentration of 1%, 5%, and 10%. Measuring instrument of this research uses calipers with denominations of millimeters (mm). Based on the results of the Mann Whitney test, there was a significant difference in inhibition of chitosan gel on the scale of milkfish 1%, 5%, and 10% against the Aggregatibacter actinomycetemcomitans & Porphyromonas gingivalis gel (p <0.005), and based on the Kruskal Wallis test, it was found that the higher concentration of gel milkfish scales, the higher the average inhibition power. It was concluded that milkfish scales gel chitosan (Chanos chanos) can inhibit the growth of Aggregatibacter actinomycetemcomitans & Porphyromonas gingivalis and the higher the concentration of chitosan gel in milkfish scales, the higher the inhibition zone produced.
- Subjects
CHITOSAN; PORPHYROMONAS gingivalis; ACTINOBACILLUS actinomycetemcomitans; PATHOGENIC bacteria; BACTERIA; MEASURING instruments
- Publication
Systematic Reviews in Pharmacy, 2020, Vol 11, Issue 6, p836
- ISSN
0975-8453
- Publication type
Article
- DOI
10.31838/srp.2020.6.121