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- Title
Pure Red-Cell Aplasia of Long Duration after Major ABO-Incompatible Bone Marrow Transplantation.
- Authors
Volin, Liisa; Ruutu, Tapani
- Abstract
We describe a patient with an exceptionally long-lasting red-cell aplasia of 330 days following ABO-incompatible bone marrow transplantation (BMT). Before BMT, the anti-B titre was high, 1:1,024, and it was only temporarily reduced by extensive plasma exchange. The anti-B titre remained above the level of 1:64 for 270 days, and host-derived isoagglutinin could still be detected 3 years after BMT. In vitro bone marrow cultures during the red-cell aplasia showed greatly reduced numbers or total absence of CFU-E, while the number of BFU-E colonies was only moderately subnormal. Six years after BMT, bone marrow and peripheral-blood cell counts are normal. Copyright © 1990 S. Karger AG, Basel
- Publication
Acta Haematologica, 1990, Vol 84, Issue 4, p195
- ISSN
0001-5792
- Publication type
Article
- DOI
10.1159/000205063