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- Title
Antimicrobial susceptibility pattern of <italic>Staphylococcus aureus</italic> isolates from clinical specimens at Kenyatta National Hospital.
- Authors
Gitau, Wilfred; Masika, Moses; Musyoki, Moses; Museve, Beatrice; Mutwiri, Titus
- Abstract
Objective: To determine antibiotic susceptibility pattern of <italic>S. aureus</italic> isolates from clinical specimens collected from patients at Kenyatta National Hospital from March 2014–February 2016, and to determine the prevalence and quarterly trends of MRSA throughout the study period. Results: A total of 944 <italic>S. aureus</italic> isolates were analyzed. High sensitivity of <italic>S. aureus</italic> was observed for quinupristin/dalfopristin (100%), tigecycline (98.2), imipenem (98%), nitrofurantoin (97.6%), linezolid (97.3%), teicoplanin (97.1%) and vancomycin (95.1%). High resistance was recorded against penicillin G (91.9%), trimethoprim/sulfamethoxazole (56.9%) and tetracycline (33.2%). MRSA prevalence among the patients at KNH was 27.8%. Highest proportion (80%) of MRSA was in burns unit. Both MRSA and MSSA were highly susceptible to quinupristin/dalfopristin, tigecycline, linezolid, nitrofurantoin, ampicillin/sulbactam and vancomycin and showed high resistance to commonly used antibiotics such as gentamycin, erythromycin, levofloxacin and tetracycline. A majority of isolates were from pus specimen (68%).
- Subjects
MICROBIAL sensitivity tests; STAPHYLOCOCCUS aureus; QUINUPRISTIN; DALFOPRISTIN; TEICOPLANIN
- Publication
BMC Research Notes, 2018, Vol 11, Issue 1, p1
- ISSN
1756-0500
- Publication type
Article
- DOI
10.1186/s13104-018-3337-2