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- Title
Alteraciones de la función tiroidea en niños con insuficiencia renal crónica.
- Authors
Garrido-Magaña, E.; Heyser-Ortiz, S. E.; Aguilar-Kitsu, A.; Mendoza-Guevara, L.; Ramírez-Rivera, A.; Nishimura-Meguro, E.; García, H. J.; Villasís-Keever, M. A.
- Abstract
Objectives. To determine the frequency and type of thyroid dysfunction in children with chronic renal failure (CRF) in peritoneal dialysis (PD) or hemodialysis (HD); and to establish the accuracy of the presence of goiter to identify patients with CRF and thyroid dysfunction. Patients and methods: This is a crosssectional study performed in a tertiary pediatric medical care center. CRF patients younger than 17 years old, with more than three months in PD or HD were included. All patients were assessed regarding their growth and sexual development; thyroid dysfunction was evaluated by serum concentration of thyrotropin (TSH), thyroxine (T4L) and triiodothyronine (T3T). Results: 50 patients were included, 25 were male, and mean age was 13 years old. There were 14 (28%) patients with thyroid dysfunction; nine had subclinical hypothyroidism, three patients had euthyroid sick syndrome and two primary hypothyroidism. Thirteen patients had goiter: seven had thyroid dysfunction and in six patients the thyroid function was normal. The sensitivity of goiter to detect thyroid dysfunction was 50% and the specificity was 83.3%. The two patients with the greatest delay in their growth were hypothyroid. Conclusions: Given the high frequency of thyroid dysfunction in children with CRF, these patients need a systematic screening, in order to improve their quality of care.
- Subjects
CHRONIC kidney failure in children; PERITONEAL dialysis; THYROID disease diagnosis; PEDIATRIC diagnosis; HYPOTHYROIDISM in children; CHILDREN'S hospitals; PEDIATRICS
- Publication
Nefrologia, 2009, Vol 29, Issue 5, p449
- ISSN
0211-6995
- Publication type
Article