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- Title
Activation of natural killer T cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes.
- Authors
Sharif, Shayan; Arreaza, Guillermo A.; Zucker, Peter; Mi, Qing-Sheng; Sondhi, Jitin; Naidenko, Olga V.; Kronenberg, Mitchell; Koezuka, Yasuhiko; Delovitch, Terry L.; Gombert, Jean-Marc; Leite-De-Moraes, Maria; Gouarin, Christine; Zhu, Ren; Hameg, Agathe; Nakayama, Toshinori; Taniguchi, Masaru; Lepault, Françoise; Lehuen, Agnès; Bach, Jean-François
- Abstract
Cites a study stating that the activation of natural killer T (NKT) cells by α-galactosylceramide treatment prevents the onset and recurrence of autoimmune type 1 diabetes. Infusion of NKT cell enriched thymocyte preparations in non-obese diabetic mice; Mechanism of functioning of these cells.
- Subjects
DIABETES; T cells; KILLER cells; LABORATORY mice
- Publication
Nature Medicine, 2001, Vol 7, Issue 9, p1057
- ISSN
1078-8956
- Publication type
Article
- DOI
10.1038/nm0901-1057