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- Title
The Biological Role of Platelet Derivatives in Regenerative Aesthetics.
- Authors
Santos, Lorena Cristina; Lana, Giselle Lobo; Santos, Gabriel Silva; Visoni, Silvia Beatriz Coutinho; Brigagão, Rayssa Junqueira; Santos, Napoliane; Sobreiro, Rafaela; da Cruz Silva Reis, Andreza; Rodrigues, Bruno Lima; Ferrari, Sabrina; Tambeli, Claudia Herrera; Lana, José Fábio
- Abstract
Bioproducts derived from platelets have been extensively used across various medical fields, with a recent notable surge in their application in dermatology and aesthetic procedures. These products, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), play crucial roles in inducing blood vessel proliferation through growth factors derived from peripheral blood. PRP and PRF, in particular, facilitate fibrin polymerization, creating a robust structure that serves as a reservoir for numerous growth factors. These factors contribute to tissue regeneration by promoting cell proliferation, differentiation, and migration and collagen/elastin production. Aesthetic medicine harnesses these effects for diverse purposes, including hair restoration, scar treatment, striae management, and wound healing. Furthermore, these biological products can act as adjuvants with other treatment modalities, such as laser therapy, radiofrequency, and microneedling. This review synthesizes the existing evidence, offering insights into the applications and benefits of biological products in aesthetic medicine.
- Subjects
BIOLOGICAL products; PLATELET-rich fibrin; PLATELET-rich plasma; REGENERATION (Biology); WOUND healing; COSMETIC dermatology; SKIN regeneration
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 11, p5604
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25115604