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- Title
Genetic and Epigenetic Factors in Gestational Diabetes Mellitus Pathology.
- Authors
Ustianowski, Łukasz; Udzik, Jakub; Szostak, Joanna; Gorący, Anna; Ustianowska, Klaudia; Pawlik, Andrzej
- Abstract
Gestational diabetes (GDM) is the carbohydrate intolerance occurring during pregnancy. The risk factors of GDM include obesity, advanced maternal age, polycystic ovary syndrome, multigravidity, a sedentary lifestyle, and pre-existing hypertension. Additionally, complex genetic and epigenetic processes are also believed to play a crucial role in the development of GDM. In this narrative review, we discuss the role of genetic and epigenetic factors in gestational diabetes mellitus pathogenesis.
- Subjects
GESTATIONAL diabetes; MATERNAL age; CARBOHYDRATE intolerance; EPIGENETICS; POLYCYSTIC ovary syndrome; PATHOLOGY
- Publication
International Journal of Molecular Sciences, 2023, Vol 24, Issue 23, p16619
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms242316619