We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Triglyceride glucose-body mass index and hypertension risk in iranian adults: a population-based study.
- Authors
Nikbakht, Hamid Reza; Najafi, Farid; Shakiba, Ebrahim; Darbandi, Mitra; Navabi, Jafar; Pasdar, Yahya
- Abstract
Background: Insulin resistance (IR) and obesity are risk factors for hypertension; triglyceride-glucose (TyG) is known as a surrogate for IR. The present study investigated the association between the triglyceride-glucose body mass index (TyG-BMI) index and the risk of hypertension in Iranian adults. Methods: This study was conducted on a sample of 8,610 participants from the baseline phase of the Ravansar non- communicable diseases (RaNCD) in Iran. A logistic regression model was used to evaluate the relationship between TyG-BMI and hypertension. Receiver operating characteristic (ROC) curve analysis was conducted to estimate the predictive power of TyG-BMI for hypertension. Results: A total of 4176 men and 4434 women with an average age of 46.74 years were examined. The anthropometric indices were significantly higher in hypertensive than normotensive subjects (P < 0.001). The level of physical activity was significantly higher in the bottom quartiles (P < 0.001). The odds of hypertension in the highest quartile and 3.10 (95% CI: 2.28, 4.16) times significantly higher than the bottom quartile of the TyG-BMI index. The discriminating ability of TyG-BMI to predict blood pressure was 61% (AUC: 0.61; 95% CI: 0.57, 0.63), and higher than BMI and TyG. Conclusion: The TyG-BMI index is associated with an increase in the odds of hypertension. Therefore, the TyG-BMI index can be a new clinical index for early diagnosis of hypertension. Lifestyle modifications such as weight control through physical activity and a healthy diet can help improve IR and prevent hypertension.
- Subjects
IRAN; HYPERTENSION risk factors; ANALYSIS of triglycerides; GLUCOSE analysis; OBESITY; FOOD habits; CONFIDENCE intervals; ANTHROPOMETRY; RISK assessment; PHYSICAL activity; DESCRIPTIVE statistics; RESEARCH funding; BODY mass index; LOGISTIC regression analysis; RECEIVER operating characteristic curves; ODDS ratio; INSULIN resistance; EARLY diagnosis
- Publication
BMC Endocrine Disorders, 2023, Vol 23, Issue 1, p1
- ISSN
1472-6823
- Publication type
Article
- DOI
10.1186/s12902-023-01411-5