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- Title
Completion of tuberculosis preventive therapy and associated factors among clients on antiretroviral therapy at Debre Berhan town health facilities, North Shoa Zone, Ethiopia.
- Authors
Tegegnework, Alebachew Zewdu; Aemiro, Muluken Tessema; Bilchut, Awraris Hailu; Mekuria, Abinet Dagnaw; Yehualashet, Sisay Shewasinad
- Abstract
Background: Tuberculosis preventive therapy is vital in caring for HIV-positive individuals, as it prevents the progression from latent tuberculosis infection to tuberculosis disease. The aim of the study is to assess the completion of tuberculosis preventive therapy and associated factors among clients receiving antiretroviral therapy in Debre Berhan town, Ethiopia, in 2022. Method: Institutional based cross sectional study was conducted. Random sampling methods were used to select both study participants and health facilities. Both bivariate and multivariate logistic regression analyses were performed. P-values less than 0.05 were statistically significant. Result: The study found that, 83% of participants were completed tuberculosis preventive therapy. Completed tuberculosis preventive therapy was associated with no adverse drug events, taking first-line ART, and good ART adherence. Conclusion: According to the Ethiopian ART guidelines, the study found a low completion rate of tuberculosis preventive therapy among HIV-positive clients on antiretroviral therapy. Factors like no adverse drug events, first-line antiretroviral regimen, and good adherence were significantly associated with completing tuberculosis preventive therapy.
- Subjects
ETHIOPIA; DRUG therapy for tuberculosis; TUBERCULOSIS epidemiology; TUBERCULOSIS prevention; HIV infection epidemiology; HIV prevention; CROSS-sectional method; PATIENT compliance; HEALTH services accessibility; ANTIRETROVIRAL agents; STATISTICAL sampling; MULTIPLE regression analysis; AT-risk people; HIV infections; DESCRIPTIVE statistics; ANTITUBERCULAR agents; PSYCHOLOGY of HIV-positive persons; STATISTICS; HEALTH facilities; DRUGS
- Publication
AIDS Research & Therapy, 2024, Vol 21, Issue 1, p1
- ISSN
1742-6405
- Publication type
Article
- DOI
10.1186/s12981-024-00629-0