We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Immune Modulation by Mesenchymal Stem Cells.
- Authors
Francesco Bifari; Veronica Lisi; Elda Mimiola; Annalisa Pasini; Mauro Krampera
- Abstract
SummaryMesenchymal stem cells (MSCs) and their stromal progeny may be considered powerful regulatory cells, a sort of dendritic cell counterpart, which influence all the main immune effectors and functional roles in vivo, as well as potential applications in the treatment of a number of human immunological diseases. By choosing MSC tissue origin, cell dose, administration route, and treatment schedule, all the potential side effects related to MSC use, including tumor growth enhancement, have to be well considered to maximize the benefits of MSC-dependent immune regulation without significant risks for the patients.Copyright © 2008 S. Karger AG, Basel
- Subjects
STEM cell research; IMMUNOREGULATION; CELLULAR control mechanisms; DENDRITIC cells; IMMUNOLOGIC diseases; MEDICAL care; THERAPEUTICS
- Publication
Transfusion Medicine & Hemotherapy, 2008, Vol 35, Issue 3, p194
- ISSN
1660-3796
- Publication type
Article
- DOI
10.1159/000128968