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- Title
Recurrence rate and associated factors of borderline ovarian tumors in the south of Vietnam.
- Authors
Vo, Tuan M.; Duong, Kim A.; Tran, Ly T.‐H.; Bui, Thanh C.
- Abstract
Aim: This study aimed to determine the recurrence rate and related risk factors of borderline ovarian tumors (BOT). Methods: We conducted a retrospective cohort study with 433 patients who were surgically treated for primary BOT at Tu Du Hospital from 11/2008 to 09/2015. We used the life table method to estimate the cumulative recurrence rate. We used the log–rank test and Cox proportional hazard model to determine recurrence‐associated factors. Results: Median follow‐up time was 43 months (range: 3–105 months). Eighteen patients developed recurrence. The cumulative BOT recurrence rates at year 1, 2, 3 and 4 were 1.2% (95% confidence interval [CI] = 0.5–2.8), 3.0% (95% CI = 1.7–5.2), 4.6% (95% CI = 2.9–7.4), and 5.1% (95% CI = 3.2–8.0), respectively. In the final multivariate model, a higher recurrence rate was significantly associated with primary tumor stages (stage I vs stages II and III, hazards ratio [HR] = 4.44, 95% CI = 1.60–12.38), pre‐operative tumor's capsule rupture (HR = 4.14, 95% CI = 1.78–9.64), and cystectomy (HR = 5.33, 95% CI = 1.43–19.91). Conclusion: The overall BOT recurrence rate in women in southern Vietnam was moderate. Primary tumor stage, capsule rupture, and cystectomy were main factors associated with BOT recurrence. Appropriate follow‐up strategies for patients with high‐risk factors are needed for early detection and management of recurrence.
- Subjects
VIETNAM; CONFIDENCE intervals; CANCER relapse; HOSPITALS; PATIENT aftercare; LONGITUDINAL method; MEDICAL protocols; MULTIVARIATE analysis; OVARIAN tumors; POPULATION geography; RISK assessment; TIME; TUMOR classification; PROPORTIONAL hazards models; RETROSPECTIVE studies; PREOPERATIVE period; DESCRIPTIVE statistics; CYSTECTOMY; EARLY detection of cancer; LOG-rank test; CANCER treatment; CANCER risk factors
- Publication
Journal of Obstetrics & Gynaecology Research, 2019, Vol 45, Issue 10, p2055
- ISSN
1341-8076
- Publication type
Article
- DOI
10.1111/jog.14072