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- Title
Successful therapeutic plasma exchange in a 3.2-kg body weight neonate with atypical hemolytic uremic syndrome.
- Authors
Jung, Sunkyung; Kang, Eun-Suk; Ki, Chang-Seok; Kim, Dae-Won; Paik, Kyung-Hoon; Chang, Yun Sil
- Abstract
Atypical hemolytic uremic syndrome (aHUS) is a rare form of complement dysregulation disease, and recently various reports have shown that it is associated with one or more mutations in the complement regulatory genes including complement factor H ( CFH). Plasma exchange is a therapeutic option for adult patients, but not for a very young infant because of a potential side effect of therapeutic plasma exchange (TPE) itself. Herein, we describe a case of successful treatment of early onset aHUS associated with a novel CFH mutation with total 21 sessions of TPE over a period of 46 days in 3.2 kg 23-day-old neonate. J. Clin. Apheresis, 2011. © 2011 Wiley-Liss, Inc.
- Publication
Journal of Clinical Apheresis, 2011, Vol 26, Issue 3, p162
- ISSN
0733-2459
- Publication type
Article
- DOI
10.1002/jca.20283