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- Title
Three-component hetero-domino cyclization and copper-catalyzed double A<sup>3</sup>-coupling reaction of ethane-1,2-diamines, formaldehyde, and alkynes to afford 1,3-dipropargylimidazolidines.
- Authors
Sun, Lu; Wu, Mengying; Huang, Xi; Wang, Jiayi; Song, Gonghua
- Abstract
<graphic></graphic>A novel and efficient approach to the synthesis of 1,3-dipropargylimidazolidines via a hetero-domino cyclization and copper-catalyzed double A3-coupling reaction of ethane-1,2-diamines, formaldehyde, and alkynes has been reported. The transformation provides a useful method for the synthesis of imidazolidine derivatives.
- Subjects
COUPLING reactions (Chemistry); COPPER catalysts; RING formation (Chemistry); FORMALDEHYDE; DIAMINES; ALKYNES; IMIDAZOLIDINES
- Publication
Chemistry of Heterocyclic Compounds, 2018, Vol 54, Issue 3, p355
- ISSN
0009-3122
- Publication type
Article
- DOI
10.1007/s10593-018-2273-3