We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Association between anaemia and vitamin D insufficiency among 6- to 12-month-old infants: implications for clinical practice.
- Authors
Boonrusmee, Sasivara; Kasemsripitak, Staporn; Navykarn, Thitiporn; Jaruratanasirikul, Somchit
- Abstract
Background Anaemia and vitamin D insufficiency (VDI) are among the most common nutritional problems. Anaemia screening is routinely performed; however, screening for VDI is not usually recommended. Objectives To study the association between anaemia and VDI and identify the risk factors for VDI. Methods We conducted a cross-sectional study of 120 infants aged 6–12 months attending a well-child clinic at Songklanagarind Hospital between December 2020 and November 2021. Sociodemographic data and 24-h food records were also collected. Blood samples were obtained for complete blood count and 25-hydroxyvitamin D [25(OH)D] levels. Logistic regression analysis was used to determine risk factors for VDI. Results The mean 25(OH)D level was 22.2 ± 8.9 ng/mL in anaemic infants and 27.2 ± 9.6 ng/mL in non-anaemic infants (P value 0.01). The median (IQR) Hb level was 11.1 g/dL (10.3, 11.4) in the VDI group and 11.4 g/dL (11, 12.1) in the non-VDI group (P value 0.002). The proportion of breastfed infants was higher in infants with anaemia (80%) (P < 0.001) and VDI (85.3%) (P < 0.001). Sunlight exposure <15 min/day (odds ratio [OR] 3.84; 95% confidence interval [CI]: 1.23–12.00; P = 0.020) was a risk factor, and vitamin D intake (OR 0.37; 95% CI: 0.20–0.74; P = 0.004) was a protective factor for VDI. Conclusion Infants with anaemia, short duration of sunlight exposure, breastfeeding, low vitamin D intake, and low iron intake were more likely to be vitamin D insufficient. However, after adjustment in the multivariate analyses, only sunlight exposure and vitamin D intake were significantly associated with vitamin D insufficiency.
- Subjects
VITAMIN D; INFANTS; ANEMIA; BLOOD cell count; LOGISTIC regression analysis; ANKYLOGLOSSIA; SUNBURN
- Publication
Family Practice, 2024, Vol 41, Issue 3, p305
- ISSN
0263-2136
- Publication type
Article
- DOI
10.1093/fampra/cmad033