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- Title
Extraosseous Ewing sarcoma and peripheral primitive neuroectodermal tumor of the thyroid gland: Case report and review.
- Authors
Chirila, Magdalena; Muresan, Mihaela; Ciuleanu, Elisabeta; Cosgarea, Marcel
- Abstract
The Ewing family of tumors and peripheral primitive neuroectodermal tumor (pPNET) represent different manifestations of the same entity. Immunohistochemical and cytogenetic studies suggest that these tumors have a common origin. Ewing sarcoma is more common in bone, while pPNET is more common in soft tissues. Extraosseous Ewing sarcoma (EoES) is rare. We present the case of a 48-year-old man who presented with acute obstructive respiratory failure secondary to a large thyroid swelling. The patient was initially diagnosed with giant B-cell non-Hodgkin lymphoma and treated with chemotherapy. However, subsequent immunohistochemical staining of biopsy specimens revealed that the patient actually had EoES/pPNET of the thyroid gland. We performed a nearly complete surgical resection of the tumor plus a total laryngectomy and resection of five tracheal rings. However, the patient died of a cerebral metastasis 1 month later after he had completed one cycle of postoperative chemotherapy.
- Subjects
EWING'S sarcoma; THYROID gland tumors
- Publication
ENT: Ear, Nose & Throat Journal, 2013, Vol 92, Issue 4/5, pE3
- ISSN
0145-5613
- Publication type
Article
- DOI
10.1177/014556131309200419