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- Title
CD30‐positive primary cutaneous anaplastic large cell lymphoma with coexistent pseudocarcinomatous hyperplasia.
- Authors
Kreuter, A.; Pantelaki, I.; Michalowitz, A.‐L.; Wieland, U.; Cerroni, L.; Oellig, F.; Tigges, C.
- Abstract
Summary: CD30‐positive primary cutaneous anaplastic large cell lymphoma (C‐ALCL) is an indolent type of cutaneous lymphoma with favourable clinical prognosis. Pseudocarcinomatous hyperplasia (PCH) is a rare benign epithelial condition that can resemble invasive squamous cell carcinoma both clinically and histopathologically. PCH predominantly occurs in CD30‐positive lymphoproliferative disorders. We report a 75‐year‐old woman with PCH in a multifocal C‐ALCL located on the scalp and right retroauricular area, which rapidly responded to treatment with psoralen ultraviolet A photochemotherapy. Comprehensive virological analyses for potential oncogenic viruses, including Epstein–Barr virus, human herpesvirus‐8, human papillomaviruses, the recently discovered cutavirus and nine different human polyomaviruses, were negative.
- Subjects
CD30 antigen; CD antigens; HISTOPATHOLOGY; LYMPHOMAS; CELL proliferation; ANAPLASTIC lymphoma kinase
- Publication
Clinical & Experimental Dermatology, 2018, Vol 43, Issue 5, p585
- ISSN
0307-6938
- Publication type
Article
- DOI
10.1111/ced.13416