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- Title
Imaging findings in renal lymphoma.
- Authors
Medar, C.; Grasu, M. C.; Baston, C.; Baston, O. M.; Sinescu, I.
- Abstract
Introduction and objectives. The aim of this paper is to systematize and illustrate distinct imaging patterns and lesions distribution seen in renal lymphomas and to discuss the differential diagnosis with other renal tumors. Materials and methods. We realized a retrospective study over a period of 12 years from the cases investigated by CT or MRI in our hospital and diagnosed with a lymphoproliferative disease. Of the 3290 patients found, a total of 48 showed renal lymphoma. There was pathological confirmation for all patients, either node biopsy or after nephrectomy. All patients had at least two CT / MRI examinations. Indications for CT examination were: disease staging, follow-up at 6 or 12 months, clinical suspicion of recurrence and evaluation of renal or other organs lesions. Follow-up interval varied from four months to four years. MRI examination was performed only in two patients with iodinated contrast material allergy. Results. The most common imaging appearance of renal lymphomas is that of homogeneous, isodense (non-enhanced CT) and hypoattenuated (contrast-enhanced CT) masses compared with normal parenchyma. We found a wide variety of manifestation: multiple bilateral (52%) or unilateral masses (13%), a solitary nodular lesion (8%) or infiltrative lesions (13%), contiguous retroperitoneal extension (6%) or masses in the perirenal space (8%). Conclusions. Contrast enhanced CT is useful in: detection and characterization of renal involvements in patients with lymphoma, disease staging, follow-up and response after therapy and differential diagnosis with other renal masses. Histological confirmation of disease and the presence of bilateral renal nodular lesions associated with other extra-nodal involvements can establish the diagnosis of renal lymphoma. Otherwise renal biopsy is necessary.
- Subjects
DIAGNOSTIC imaging; KIDNEY tumors; LYMPHOMA diagnosis; DIAGNOSIS
- Publication
Romanian Journal of Urology, 2015, Vol 14, Issue 4, p42
- ISSN
1223-0650
- Publication type
Article