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Variable effects of the APOC3 –482C > T variant on insulin, glucose and triglyceride concentrations in different ethnic groups.
Published in:
Diabetologia, 2001, v. 44, n. 2, p. 245, doi. 10.1007/s001250051607
By:
- Waterworth, D. M.;
- Talmud, P. J.;
- Humphries, S. E.;
- Wicks, P. D.;
- Sagnella, G. A.;
- Strazzullo, P.;
- Alberti, K. G. M. M.;
- Cook, D. G.;
- Cappuccio, F. P.
Publication type:
Article
Variation in the PPARα gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects.
Published in:
Diabetologia, 2000, v. 43, n. 5, p. 673, doi. 10.1007/s001250051357
By:
- Flavell, D. M.;
- Torra, I. Pineda;
- Jamshidi, Y.;
- Evans, D.;
- Diamond, J. R.;
- Elkeles, R. S.;
- Bujac, S. R.;
- Miller, G.;
- Talmud, P. J.;
- Staels, B.;
- Humphries, S. E.
Publication type:
Article
Mutation detection rate and spectrum in familial hypercholesterolaemia patients in the UK pilot cascade project.
Published in:
Clinical Genetics, 2010, v. 77, n. 6, p. 572, doi. 10.1111/j.1399-0004.2009.01356.x
By:
- Taylor, A.;
- Wang, D.;
- Patel, K.;
- Whittall, R.;
- Wood, G.;
- Farrer, M.;
- Neely, R. D. G.;
- Fairgrieve, S.;
- Nair, D.;
- Barbir, M.;
- Jones, J. L.;
- Egan, S.;
- Everdale, R.;
- Lolin, Y.;
- Hughes, E.;
- Cooper, J. A.;
- Hadfield, S. G.;
- Norbury, G.;
- Humphries, S. E.
Publication type:
Article
Mutation screening in patients for familial hypercholesterolaemia (ADH).
Published in:
Clinical Genetics, 2010, v. 77, n. 1, p. 97, doi. 10.1111/j.1399-0004.2009.01279.x
By:
- Taylor, A.;
- Patel, K.;
- Tsedeke, J.;
- Humphries, S. E.;
- Norbury, G.
Publication type:
Article
Multiplex ligation-dependent probe amplification analysis to screen for deletions and duplications of the LDLR gene in patients with familial hypercholesterolaemia.
Published in:
Clinical Genetics, 2009, v. 76, n. 1, p. 69, doi. 10.1111/j.1399-0004.2009.01168.x
By:
- Taylor, A.;
- Martin, B.;
- Wang, D.;
- Patel, K.;
- Humphries, S. E.;
- Norbury, G.
Publication type:
Article
Multiplex MassARRAY spectrometry (iPLEX) produces a fast and economical test for 56 familial hypercholesterolaemia-causing mutations.
Published in:
Clinical Genetics, 2008, v. 74, n. 5, p. 463, doi. 10.1111/j.1399-0004.2008.01071.x
By:
- Wright, W. T.;
- Heggarty, S. V.;
- Young, I. S.;
- Nicholls, D. P.;
- Whittall, R.;
- Humphries, S. E.;
- Graham, C. A.
Publication type:
Article
Multiplex ARMS analysis to detect 13 common mutations in familial hypercholesterolaemia.
Published in:
Clinical Genetics, 2007, v. 71, n. 6, p. 561, doi. 10.1111/j.1399-0004.2007.00807.x
By:
- Taylor, A.;
- Tabrah, S.;
- Wang, D.;
- Sozen, M.;
- Duxbury, N.;
- Whittall, R.;
- Humphries, S. E.;
- Norbury, G.
Publication type:
Article
Interaction of the cholesteryl ester transfer protein I405V polymorphism with alcohol consumption in smoking and non-smoking healthy men, and the effect on plasma HDL cholesterol and apoAI concentration.
Published in:
Clinical Genetics, 1997, v. 51, n. 1, p. 15, doi. 10.1111/j.1399-0004.1997.tb02407.x
By:
- Gudnason, V.;
- Thormar, K.;
- Humphries, S. E.
Publication type:
Article
Association of genetic variation at the β-fibrinogen gene locus and plasma fibrinogen evels; interaction between allele frequency of the G/A.
Published in:
Clinical Genetics, 1996, v. 50, n. 4, p. 184, doi. 10.1111/j.1399-0004.1996.tb02623.x
By:
- Thomas, A. E.;
- Green, F. R.;
- Humphries, S. E.
Publication type:
Article
Lack of association of angiotensin-converting enzyme ( ACE). Gene insertion/deletion polymorphism with CAD in two Asian populations.
Published in:
Clinical Genetics, 1996, v. 50, n. 3, p. 121, doi. 10.1111/j.1399-0004.1996.tb02365.x
By:
- Saha, N.;
- Talmud, P. J.;
- Tay, J. S. H.;
- Humphries, S. E.;
- Basair, J.
Publication type:
Article
DNA polymorphisms of the apolipoprotein B gene are associated with obesity and serum lipids in healthy Indians in Singapore.
Published in:
Clinical Genetics, 1993, v. 44, n. 3, p. 113, doi. 10.1111/j.1399-0004.1993.tb03861.x
By:
- Saha, N.;
- Tay, J. S. H.;
- Heng, G. K.;
- Humphries, S. E.
Publication type:
Article
Possibilities of DNA Analysis for the Detection of Predisposition to Thrombotic Disease.
Published in:
Annals of the New York Academy of Sciences, 1992, v. 667, n. 1, p. 332, doi. 10.1111/j.1749-6632.1992.tb51634.x
By:
- THOMAS, A. E.;
- GREEN, F. R.;
- DAWSON, S. J.;
- LANE, A.;
- HENNEY, A. M.;
- KELLEHER, C. H.;
- WILKES, H. C.;
- BRENNAN, P. J.;
- CRUICKSHANK, J. K.;
- HAMSTEN, A.;
- WIMAN, B.;
- MEADE, T. W.;
- HUMPHRIES, S. E.
Publication type:
Article
ANALYSIS OF THE ASSOCIATION OF A HEAT SHOCK PROTEIN70-1 GENE PROMOTER POLYMORPHISM WITH MYOCARDIAL INFARCTION AND CORONARY RISK TRAITS.
Published in:
Disease Markers, 1998, v. 13, n. 4, p. 227, doi. 10.1155/1998/235151
By:
- BOLLA, M. K.;
- MILLER, G. J.;
- YELLON, D. M.;
- EVANS, A.;
- LUC, G.;
- CAMBOU, J. P.;
- ARVEILER, D.;
- CAMBIEN, F.;
- LATCHMAN, D. S.;
- HUMPHRIES, S. E.;
- DAY, I. N. M.
Publication type:
Article
DETECTION OF THE LOW DENSITY LIPOPROTEIN RECEPTOR GENE PVUII INTRON 15 POLYMORPHISM USING THE POLYMERASE CHAIN REACTION: ASSOCIATION WITH PLASMA LIPID TRAITS IN HEALTHY MEN AND WOMEN.
Published in:
Disease Markers, 1998, v. 13, n. 4, p. 209, doi. 10.1155/1998/842051
By:
- GUDNASON, V.;
- ZHOU, T.;
- THORMAR, K.;
- BAEHRING, S.;
- COOPER, J.;
- MILLER, G.;
- HUMPHRIES, S. E.;
- SCHUSTER, H.
Publication type:
Article
Familial hypercholesterolaemia workshop for leveraging point-of-care testing and personalised medicine in association with the Lipid and Atherosclerosis Society of Southern Africa.
Published in:
Cardiovascular Journal of Africa, 2019, v. 30, n. 5, p. 297, doi. 10.5830/CVJA-2019-055
By:
- Marais, A. D.;
- Kotze, M. J.;
- Raal, F. J.;
- Khine, A. A.;
- Talmud, P. J.;
- Humphries, S. E.
Publication type:
Article
The use of a highly informative CA repeat polymorphism within the abetalipoproteinaemia locus (4q22-24).
Published in:
1997
By:
- Heath, K E;
- Luong, L A;
- Leonard, J V;
- Chester, A;
- Shoulders, C C;
- Scott, J;
- Middleton-Price, H R;
- Humphries, S E;
- Talmud, P J
Publication type:
journal article
Effects of genetic variation on chromatin structure and the transcriptional machinery: analysis of the IL6 gene locus.
Published in:
Genes & Immunity, 2012, v. 13, n. 7, p. 583, doi. 10.1038/gene.2012.32
By:
- Smith, A J P;
- Zheng, D;
- Palmen, J;
- Pang, D X;
- Woo, P;
- Humphries, S E
Publication type:
Article
Interleukin-18 genetics and inflammatory disease susceptibility.
Published in:
Genes & Immunity, 2007, v. 8, n. 2, p. 91, doi. 10.1038/sj.gene.6364366
By:
- Thompson, S. R.;
- Humphries, S. E.
Publication type:
Article
Novel IL-6 haplotypes and disease association.
Published in:
Genes & Immunity, 2005, v. 6, n. 4, p. 367, doi. 10.1038/sj.gene.6364186
By:
- Fife, M S;
- Ogilvie, E M;
- Kelberman, D;
- Samuel, J;
- Gutierrez, A;
- Humphries, S E;
- Woo, P
Publication type:
Article
Two Promoter Polymorphisms Regulating Interleukin-6 Gene Expression Are Associated with Circulating Levels of C-Reactive Protein and Markers of Bone Resorption in Postmenopausal Women.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 1, p. 255, doi. 10.1210/jc.2002-020092
By:
- FERRARI, S. L.;
- AHN-LUONG, L.;
- GARNERO, P.;
- HUMPHRIES, S. E.;
- GREENSPAN, S. L.
Publication type:
Article
Census of clinics providing specialist lipid services in the United Kingdom.
Published in:
Journal of Public Health, 2004, v. 26, n. 4, p. 353, doi. 10.1093/pubmed/fdh176
By:
- Marks, D.;
- Thorogood, M.;
- Farrer, J. M.;
- Humphries, S. E.
Publication type:
Article
Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel.
Published in:
Journal of Internal Medicine, 2006, v. 259, n. 3, p. 247, doi. 10.1111/j.1365-2796.2006.01616.x
By:
- Barter, P. J.;
- Ballantyne, C. M.;
- Carmena, R.;
- Cabezas, M. Castro;
- Chapman, M. John;
- Couture, P.;
- de Graaf, J.;
- Durrington, P. N.;
- Faergeman, O.;
- Frohlich, J.;
- Furberg, C. D.;
- Gagne, C.;
- Haffner, S. M.;
- Humphries, S. E.;
- Jungner, I.;
- Krauss, R. M.;
- Kwiterovich, P.;
- Marcovina, S.;
- Packard, C. J.;
- Pearson, T. A.
Publication type:
Article
The molecular genetics of cardiovascular disease: clinical implications.
Published in:
2003
By:
- Stephens, J. W.;
- Humphries, S. E.
Publication type:
journal article
Cascade screening for familial hypercholesterolaemia: implications of a pilot study for national screening programmes.
Published in:
Journal of Medical Screening, 2006, v. 13, n. 3, p. 156, doi. 10.1258/096914106778440617
By:
- Marks, D.;
- Thorogood, M.;
- Neil, S. M.;
- Humphries, S. E.;
- Neil, H. A. W.
Publication type:
Article
Interleukin 6 and the prognosis of abdominal aortic aneurysms.
Published in:
British Journal of Surgery, 2001, v. 88, n. 4, p. 598, doi. 10.1046/j.1365-2168.2001.01757-11.x
By:
- Jones, K. G.;
- Brown, L. C.;
- Brull, D. J.;
- Humphries, S. E.;
- Greenhalgh, R. M.;
- Powell, J. T.
Publication type:
Article
Influence of type III collagen genotype on aortic diameter and disease.
Published in:
British Journal of Surgery, 1993, v. 80, n. 10, p. 1246, doi. 10.1002/bjs.1800801008
By:
- Powell, J. T.;
- Adamson, J.;
- Macsweeney, S. T. R.;
- Greenhalgh, R. M.;
- Humphries, S. E.;
- Henney, A. M.
Publication type:
Article
Development of a high-resolution melting method for mutation detection in familial hypercholesterolaemia patients.
Published in:
Annals of Clinical Biochemistry, 2010, v. 47, n. 1, p. 44, doi. 10.1258/acb.2009.009076
By:
- Whittall, R. A.;
- Scartezini, M.;
- KaWah Li;
- Hubbart, C.;
- Reiner, Z.;
- Abraha, A.;
- Neil, H. A. W.;
- Dedoussis, G.;
- Humphries, S. E.
Publication type:
Article
Family tracing to identify patients with Familial Hypercholesterolemia: the Second Audit of the Department of Health Familial Hypercholesterolemia Cascade Testing Project.
Published in:
Annals of Clinical Biochemistry, 2009, v. 46, n. 1, p. 24, doi. 10.1258/acb.2008.008094
By:
- Hadfield, S. G.;
- Horara, S.;
- Starr, B. J.;
- Yazdgerdi, S.;
- Marks, D.;
- Bhatnagar, D.;
- Cramb, R.;
- Egan, S.;
- Everdell, R.;
- Ferns, G.;
- Jones, A.;
- Marenah, C. B.;
- Marples, J.;
- Prinsloo, P.;
- Sneyd, A.;
- Stewart, M. F.;
- Sandle, L.;
- Wang, T.;
- Watson, M. S.;
- Humphries, S. E.
Publication type:
Article
Are patients with familial hypercholesterolaemia well managed in lipid clinics? An audit of eleven clinics from the Department of Health Familial Hypercholesterolaemia Cascade Testing project.
Published in:
Annals of Clinical Biochemistry, 2008, v. 45, n. 2, p. 199, doi. 10.1258/acb.2007.007078
By:
- Hadfield, S G;
- Horara, S;
- Starr, B J;
- Yazdgerdi, S;
- Bhatnagar, D;
- Cramb, R;
- Egan, S;
- Everdell, R;
- Ferns, G;
- Jones, A;
- Marenah, C B;
- Marples, J;
- Prinsloo, P;
- Sneyd, A;
- Stewart, M F;
- Sandle, L;
- Wang, T;
- Watson, M S;
- Humphries, S E
Publication type:
Article
Update and Analysis of the University College London Low Density Lipoprotein Receptor Familial Hypercholesterolemia Database.
Published in:
Annals of Human Genetics, 2008, v. 72, n. 4, p. 485, doi. 10.1111/j.1469-1809.2008.00436.x
By:
- Leigh, S. E. A.;
- Foster, A. H.;
- Whittall, R. A.;
- Hubbart, C. S.;
- Humphries, S. E.
Publication type:
Article
The use of Meta-Analysis Risk Estimates for Candidate Genes in Combination to Predict Coronary Heart Disease Risk.
Published in:
Annals of Human Genetics, 2007, v. 71, n. 5, p. 611, doi. 10.1111/j.1469-1809.2007.00359.x
By:
- Drenos, F.;
- Whittaker, J. C.;
- Humphries, S. E.
Publication type:
Article
Common Adiponectin Gene Variants Show Different Effects on Risk of Cardiovascular Disease and Type 2 Diabetes in European Subjects.
Published in:
Annals of Human Genetics, 2007, v. 71, n. 4, p. 453, doi. 10.1111/j.1469-1809.2006.00340.x
By:
- Gable, D. R.;
- Matin, J.;
- Whittall, R.;
- Cakmak, H.;
- Ka Wah Li;
- Cooper, J.;
- Miller, G. J.;
- Humphries, S. E.
Publication type:
Article
Polymorphisms in the Angiotensin Converting Enzyme Gene and Growth in the First Year of Life.
Published in:
Annals of Human Genetics, 2007, v. 71, n. 2, p. 176, doi. 10.1111/j.1469-1809.2006.00317.x
By:
- Hindmarsh, P. C.;
- Rodeck, C. H.;
- Humphries, S. E.
Publication type:
Article
Increase of Plasma Fibrinogen Levels and Variability with Age in a Sample of Middle Aged Healthy Men.
Published in:
Annals of Human Genetics, 2007, v. 71, n. 1, p. 43, doi. 10.1111/j.1469-1809.2006.00302.x
By:
- Drenos, F.;
- Miller, G. J.;
- Humphries, S. E.
Publication type:
Article
The Impact of ACE Genotype on Serum ACE Activity in a Black South African Male Population.
Published in:
Annals of Human Genetics, 2007, v. 71, n. 1, p. 1, doi. 10.1111/j.1469-1809.2006.00300.x
By:
- Payne, J. R.;
- Dhamrait, S. S.;
- Gohlke, P.;
- Cooper, J.;
- Scott, R. A.;
- Pitsiladis, Y. P.;
- Humphries, S. E.;
- Rayner, B.;
- Montgomery, Hugh E.
Publication type:
Article
The Significant Increase in Cardiovascular Disease Risk in APOEℇ4 Carriers is Evident Only in Men Who Smoke: Potential Relationship Between Reduced Antioxidant Status and ApoE4.
Published in:
Annals of Human Genetics, 2005, v. 69, n. 6, p. 613, doi. 10.1111/j.1529-8817.2005.00205.x
By:
- Talmud, P. J.;
- Stephens, J. W.;
- Hawe, E.;
- Demissie, S.;
- Cupples, L. A.;
- Hurel, S. J.;
- Humphries, S. E.;
- Ordovas, J. M.
Publication type:
Article
Heritability of C-Reactive Protein and Association with Apolipoprotein E Genotypes in Japanese Americans.
Published in:
Annals of Human Genetics, 2004, v. 68, n. 3, p. 179, doi. 10.1046/j.1529-8817.2004.00078.x
By:
- Austin, M. A.;
- Zhang, C.;
- Humphries, S. E.;
- Chandler, W. L.;
- Talmud, P. J.;
- Edwards, K. L.;
- Leonetti, D. L.;
- Mcneely, M. J.;
- Fujimoto, W. Y.
Publication type:
Article
Combined Segregation and Linkage Analysis of Fibrinogen Variability in Israeli Families: Evidence for Two Quantitative-trait Loci, One of Which is Linked to a Functional Variant (-58G > A) in the Promoter of the α-fibrinogen Gene.
Published in:
Annals of Human Genetics, 2003, v. 67, n. 3, p. 228, doi. 10.1046/j.1469-1809.2003.00016.x
By:
- Friedlander, Y.;
- Kark, J. D.;
- Sinnreich, R.;
- Basso, F.;
- Humphries, S. E.
Publication type:
Article
Linkage disequilibrium at the cystathionine ² synthase (CBS) locus and the association between genetic variation at the CBS locus and plasma levels of homocysteine.
Published in:
Annals of Human Genetics, 1998, v. 62, n. 6, p. 481
By:
- De STEFANO, V.;
- DEKOU, V.;
- NICAUD, V.;
- CHASSE, J. F.;
- LONDON, J.;
- STANSBIE, D.;
- HUMPHRIES, S. E.;
- GUDNASON, V.
Publication type:
Article
Genetic Regulation of Fibrinogen.
Published in:
European Heart Journal, 1995, v. 16, n. suppl_A, p. 16, doi. 10.1093/eurheartj/16.suppl_a.16
By:
- Humphries, S. E.
Publication type:
Article
SEGREGATION ANALYSIS OF COLLAGEN GENES IN TWO FAMILIES WITH JOINT HYPERMOBILITY SYNDROME.
Published in:
British Journal of Rheumatology, 1992, v. 31, n. 3, p. 169
By:
- HENNEY, A. M.;
- BROTHERTON, D. H.;
- CHILD, A. H.;
- HUMPHRIES, S. E.;
- GRAHAME, R.
Publication type:
Article
Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.
Published in:
2017
By:
- Mahdessian, H.;
- Perisic Matic, L.;
- Lengquist, M.;
- Gertow, K.;
- Sennblad, B.;
- Baldassarre, D.;
- Veglia, F.;
- Humphries, S. E.;
- Rauramaa, R.;
- Faire, U.;
- Smit, A. J.;
- Giral, P.;
- Kurl, S.;
- Mannarino, E.;
- Tremoli, E.;
- Hamsten, A.;
- Eriksson, P.;
- Hedin, U.;
- Mälarstig, A.;
- de Faire, U
Publication type:
journal article
Telomere shortening over 6 years is associated with increased subclinical carotid vascular damage and worse cardiovascular prognosis in the general population.
Published in:
2015
By:
- Baragetti, A;
- Palmen, J;
- Garlaschelli, K;
- Grigore, L;
- Pellegatta, F;
- Tragni, E;
- Catapano, A L;
- Humphries, S E;
- Norata, G D;
- Talmud, P J
Publication type:
journal article
Telomere shortening over 6 years is associated with increased subclinical carotid vascular damage and worse cardiovascular prognosis in the general population.
Published in:
Journal of Internal Medicine, 2015, v. 277, n. 4, p. 478, doi. 10.1111/joim.12282
By:
- Baragetti, A.;
- Palmen, J.;
- Garlaschelli, K.;
- Grigore, L.;
- Pellegatta, F.;
- Tragni, E.;
- Catapano, A. L.;
- Humphries, S. E.;
- Norata, G. D.;
- Talmud, P. J.
Publication type:
Article
The effect of the Interleukin-6–174G > C promoter gene polymorphism on endothelial function in healthy volunteers.
Published in:
2002
By:
- Brull, D. J.;
- Leeson, C. P. M.;
- Montgomery, H. E.;
- Mullen, M.;
- deDivitiis, M.;
- Humphries, S. E.;
- Deanfield, J. E.
Publication type:
Erratum
The effect of the Interleukin-6–174G > C promoter gene polymorphism on endothelial function in healthy volunteers.
Published in:
European Journal of Clinical Investigation, 2002, v. 32, n. 3, p. 153, doi. 10.1046/j.1365-2362.2002.00966.x
By:
- Brull, D. J;
- Lesson, C. P. M;
- Montgomery, H. E;
- Mullen, M;
- deDivitiis, M;
- Humphries, S. E;
- Deanfield, J. E
Publication type:
Article
A proposal to redefine familial combined hyperlipidaemia – Third workshop on FCHL held in Barcelona from 3 to 5 May 2001, during the Scientific Sessions of the European Society for Clinical Investigation.
Published in:
European Journal of Clinical Investigation, 2002, v. 32, n. 2, p. 71, doi. 10.1046/j.1365-2362.2002.00941.x
By:
- Sniderman, A. D;
- Castro Cabezas, M;
- Ribalta, J;
- Carmena, R;
- de Bruin, T. W. A;
- de Graaf, J;
- Erkelens, D. W;
- Humphries, S. E;
- Masana, L;
- Real, J. T;
- Talmud, P. J;
- Taskinen, M. R
Publication type:
Article
Determinants of plasminogen activator inhibitor 1 activity in treated NIDDM and its relation to a polymorphism in the plasminogen activator inhibitor 1 gene.
Published in:
1995
By:
- Panahloo, Arshia;
- Mohamed-Ali, Vidya;
- Lane, Anne;
- Green, Fiona;
- Humphries, Steve E.;
- Yudkin, John S.;
- Panahloo, A;
- Mohamed-Ali, V;
- Lane, A;
- Green, F;
- Humphries, S E;
- Yudkin, J S
Publication type:
journal article
IL-6–174G/C genotype is associated with the bone mineral density response to oestrogen replacement therapy in post-menopausal women.
Published in:
European Journal of Applied Physiology, 2004, v. 92, n. 1/2, p. 227, doi. 10.1007/s00421-004-1092-7
By:
- James, L.;
- Onambele, G.;
- Woledge, R.;
- Skelton, D.;
- Woods, D.;
- Eleftheriou, K.;
- Hawe, E.;
- Humphries, S. E.;
- Haddad, F.;
- Montgomery, H.
Publication type:
Article
Lipoprotein lipase gene mutations D9N and N291S in four pedigrees with familial combined hyperlipidaemia.
Published in:
European Journal of Clinical Investigation, 1996, v. 26, n. 8, p. 631, doi. 10.1111/j.1365-2362.1996.tb02146.x
By:
- BRUIN, T. W. A. DE;
- MAILLY, F.;
- BARLINGEN, H. H. J. J. VAN;
- FISHER, R.;
- CABEZAS, M. CASTRO;
- TALMUD, P.;
- DALLINGA-THIE, G. M.;
- HUMPHRIES, S. E.
Publication type:
Article

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