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- Title
Can Short Anogenital Distance Cause Chronic Prostatitis?
- Authors
Verit, Ayhan; Verit, Fatma Ferda
- Abstract
Chronic prostatitis/Chronic pelvic pain syndromes (CP/CPPS) are a widespread pathology with unknown etiology without a proved treatment algorithm. Neurologic, endocrine and immune systems, and oxidative stress, infections are ranked in the physiopathology. Anogenital distance (AGD) as a marker for the degree of antenatal exposure of androgens that link to some disorders of androgen-sensitive tissues especially of urogenital system. In this study, we aimed a construct a hypothesis that improper development of perineum and pelvic bottom due to the insufficient embryologic androgen exposure, which can be detected by reduced AGD, can form histologic/clinic CP in adulthood through the physical forces that resulted in stretched prostate via chronic hypoxia induced oxidative stress and failed immune mechanisms. AGD, unlike the previous published ones, suggested as a real physical scale to detect narrowed pelvic bottom other than an endocrine related biomarker.
- Subjects
PROSTATITIS; PELVIC pain; ENDOCRINE system; CHRONIC pain; OXIDATIVE stress; ANUS; ANTHROPOMETRY; CHRONIC diseases; MALE reproductive organs
- Publication
Urology Journal, 2021, Vol 18, Issue 3, p353
- ISSN
1735-1308
- Publication type
letter
- DOI
10.22037/uj.v18i.6687