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- Title
Is Modified Retroperitoneal Lymph Node Dissection Alive for Clinical Stage I Non-Seminomatous Germ Cell Testicular Tumor?
- Authors
Basiri, Abbas; Ali Ghaed, Mohammad; Simforoosh, Nasser; Tabibi, Ali; Danesh, Abdolkarim; Nouralizadeh, Akbar; Kardoust Parizi, Mehdi
- Abstract
Purpose: To evaluate efficacy of modified retroperitoneal lymph node dissection (RPLND) in the management of patients with pathological stage (PS) I non-seminomatous germ cell testicular tumor (NSGCT) in a retrospective study. Materials and Methods: Between April 2002 and April 2012, 55 patients with clinical stage (CS) I NSGCT had undergone modified RPLND according to Sloan-Kettering modified RPLND template. Clinicopathological parameters, retroperitoneal relapse, and antegrade ejaculation rate were evaluated in patients with PS I. Results: Of 55 patients, 41 (74.5%) and 14 (25.5%) subjects were in PS I and II, respectively. In PS I group, the mean patients' age was 32.8 years (range, 19 to 51 years) at the end of the follow-up period. Three patients missed the follow-up; hence, were excluded from the study. Mean follow-up duration was 56 months (range, 6 to 120 months). Tumor recurrence was identified in no subjects at the end of the follow-up period. Overall peri and postoperative complication rate was 18% (7 patients). Out of 38 patients, 23 (61%) had post RPLND antegrade ejaculation at the end of the study. Conclusion: Modified template RPLND is a safe, effective, and sufficient treatment for patients with no retroperitoneal micrometastasis after the procedure. Furthermore, this strategy may obviate the need for close, expensive, and potentially harmful follow-up protocol in patients with PS I NSGCT.
- Subjects
LYMPH node surgery; SURGICAL excision; TESTICULAR cancer; METASTASIS; GERM cells
- Publication
Urology Journal, 2013, Vol 10, Issue 2, p873
- ISSN
1735-1308
- Publication type
Article