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- Title
The effectiveness of cream with Centella Asiatica and Pinus Sylvestris to treat scars and burns. Clinical Trial.
- Authors
Romo, Edelisa Moredo; Fundora, Fernanda Pastrana; Albajes, Cesar Ramírez; López, Lissette Esteris; Hana, Zelenkova
- Abstract
Background: Scars and burns are ever increasing complaints among children that turn to dermatologists to find a solution for the permanent, anaesthetic marks that they usually leave. Aim of the study: Determine how effective Cicatrix® cream (Catalysis laboratories Madrid, Spain) is to treat post-operative scars and second degree burns, and to provide patients with an alternative therapy that provides aesthetic benefits in a short period of time and has minimum adverse reactions. Material and methods: A Phase II, open-label, controlled clinical trial was organised, that included 100 patients of both genders, aged between 0 and 18 years old, who had been diagnosed as having postoperative scars and burns at the Dermatology Service at the Pediatric Hospital Juan Manuel Márquez. Scars and burns were evaluated (colour, size) several times during the clinical trial. The sample was stratified according to the type of lesion and the gender and age groups in the stratus were homogenous. The Cicatrix® cream was applied on the lesion twice a day for eight weeks. Results: 57.1% of the burns completely disappeared after 8 weeks of the treatment and 46.7% of the scars got smaller by more than 50%. There was more than 50% improvement in colour for 95.2% of the burns and 72% of the scars. 98.7% of the patients with scars and 100% of the patients with burns responded well to the treatment. There were no adverse reactions. Conclusions: Cicatrix® is an excellent therapeutic alternative to treat these problems.
- Subjects
SCOTS pine; SCARS; TREATMENT for burns &; scalds; CLINICAL trials; DERMATOLOGY; THERAPEUTICS
- Publication
Clinical Dermatology / Dermatologia Kliniczna, 2012, Vol 14, Issue 3, p105
- ISSN
1730-7201
- Publication type
Article