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- Title
Primary colorectal lymphoma in Taiwan.
- Authors
Hwang, Wei-Shou; Yao, John C. T.; Cheng, Syh-Shen; Tseng, Hui-Hwa; Hwang, W S; Yao, J C; Cheng, S S; Tseng, H H
- Abstract
<bold>Background: </bold>Sixteen patients with primary lymphoma of the colon and rectum were studied.<bold>Methods: </bold>The median age of these patients was 34 years, and 13 were men. These patients often experienced abdominal pain, diarrhea, a palpable abdominal mass, weight loss, bloody stools, and tumor of the cecum. Intermediate or high-grade lymphomas occurred in 14 patients, and 5 patients had T-cell lesions. The diagnoses were established by using laparotomy in 14 patients and colonoscopic biopsy in 2 patients. Fourteen patients had surgical resections followed by chemotherapy: cyclophosphamide, doxorubicin, vincristine, and prednisolone in 10; cyclophosphamide, vincristine, and prednisolone (COP) in 2; and cyclophosphamide, vincristine, methotrexate, and prednisolone in 1 patient. Two patients underwent biopsy alone followed by chemotherapy with COP in one and chemotherapy with prednisolone in the other.<bold>Results: </bold>The median follow-up time was 38 months (range, 2-82 months). Eight patients are alive with no evidence of disease (range, 10-82+ months). Six patients died of disease from 2 to 44 months after diagnosis. One patient who had no evidence of lymphoma died of esophageal carcinoma at 61 months. The median survival time was 59 months.<bold>Conclusions: </bold>The authors' experience with colorectal lymphoma in Taiwan is different from that reported from Japan and other countries. The patients of this study were significantly younger and many had T-cell lesions. Despite the frequently poor histologic types, surgical resection and adjuvant chemotherapy can result in long-term, disease-free survival in many patients with primary colorectal lymphoma.
- Publication
Cancer (0008543X), 1992, Vol 70, Issue 3, p575
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19920801)70:3<575::AID-CNCR2820700306>3.0.CO;2-6