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- Title
Safety of Rivaroxaban for Postoperative Venous Thromboembolism Prophylaxis Following Abdominal Body Contouring Surgery: 600 Patients.
- Authors
Vasilakis, Vasileios; Kortesis, Bill G; Bharti, Gaurav; Isakson, Matthew H; Hunstad, Joseph P
- Abstract
<bold>Background: </bold>Reducing the incidence of venous thromboembolism (VTE) following abdominal body contouring surgery remains a top priority for patient safety. There is a lack of consensus regarding the optimal chemoprophylactic agent for postoperative VTE prophylaxis, and the role of oral anticoagulants warrants further investigation.<bold>Objectives: </bold>The aim of this multisurgeon, single-institution study was to determine the safety and efficacy of a 7-day postoperative rivaroxaban regimen for VTE prophylaxis in abdominal body contouring surgery.<bold>Methods: </bold>A retrospective chart review was performed of all patients who underwent abdominoplasty, circumferential body lift, fleur-de-lis panniculectomy, or circumferential fleur-de-lis panniculectomy at our surgical center from August 2014 to November 2019. A 7-day postoperative course of once-daily 10 mg rivaroxaban, starting on postoperative day 1, was administered to every patient unless there was a contraindication. The 2 primary endpoints were the incidence of VTE and bleeding events.<bold>Results: </bold>A total of 600 patients were included in the study. There were no deaths. There were 4 (0.7%) incidents of VTE events: 2 (0.3%) patients suffered pulmonary embolus and 2 (0.3%) patients suffered a lower-extremity deep venous thrombosis. A total of 13 (2.2%) patients suffered complications related to bleeding. Of these, operative intervention for control and evacuation was required in 7 (1.2%) patients.<bold>Conclusions: </bold>A 7-day postoperative course of once-daily rivaroxaban for VTE risk reduction in abdominal body contouring surgery is associated with a low incidence of VTE events and a low risk of bleeding complications.<bold>Level Of Evidence:4: </bold>
- Subjects
PREVENTION of surgical complications; THROMBOEMBOLISM prevention; VEINS; SURGICAL complications; RETROSPECTIVE studies; ANTICOAGULANTS; THROMBOEMBOLISM
- Publication
Aesthetic Surgery Journal, 2021, Vol 41, Issue 6, p674
- ISSN
1090-820X
- Publication type
journal article
- DOI
10.1093/asj/sjaa177