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- Title
The Analysis of the Effect of Blood Transfusion on Changes of Blood Platelet Parameters in Patients with Leukemia Treated with Chemotherapy.
- Authors
He, Yangxin; Liang, Shanshan; Xu, Yali; Wan, Chunjing; Ma, Feng; Wang, Baoyan
- Abstract
Objective. To study and analyze the effect of blood transfusion on the change of blood platelet parameters in patients with leukemia treated with chemotherapy. Methods. Ninety-eight patients with leukemia treated with chemotherapy in the First Affiliated Hospital of Xi'an Jiaotong University from January 2021 to January 2022 were selected to observe the changes of platelet parameters before and after blood transfusion. Results. There was significant difference between pre-transfusion and post-transfusion indexes (platelet count, mean platelet volume, and hematocrit) (P < 0.05). After binary logistic regression analysis, the use of antibiotics (OR = 2.235), blood transfusion history (OR = 3.086), abnormal white blood cell count (OR = 1.134), and frozen plasma transfusion (OR = 3.121) were the main factors of blood platelet parameters after transfusion in leukemia patients (P < 0.05). Conclusion. Blood transfusion is beneficial to improve blood platelet parameters and prevent bleeding in patients with leukemia treated with chemotherapy. Attention should be paid to patients with risk factors for poor response to blood platelet transfusion and early intervention.
- Subjects
STATISTICS; HEMATOCRIT; BLOOD transfusion; CANCER chemotherapy; BLOOD platelets; LEUKEMIA; TREATMENT effectiveness; PRE-tests &; post-tests; CANCER patients; PLATELET count; BLOOD platelet disorders; LOGISTIC regression analysis; ODDS ratio; MEAN platelet volume
- Publication
Evidence-based Complementary & Alternative Medicine (eCAM), 2022, p1
- ISSN
1741-427X
- Publication type
Article
- DOI
10.1155/2022/2901993