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- Title
Neurocognitive Features of Mild Cognitive Impairment and Distress Symptoms in Older Adults Without Major Depression.
- Authors
Nantachai, Gallayaporn; Maes, Michael; Tran-Chi, Vinh-Long; Hemrungrojn, Solaphat; Tunvirachaisakul, Chavit
- Abstract
Objective cognitive characteristics of DSOA in participants without MDD. Neurocognition was evaluated utilizing the Cambridge Neurological Test Automated Battery (CANTAB) and memory tests. Results: This research demonstrated that CANTAB tests may differentiate between aMCI and controls. The One Touch Stockings of Cambridge, probability solved on first choice (OTS_PSFC), Rapid Visual Information Processing, A prime (RVP_ A´), and the Motor Screening Task, mean latency, were identified as the significant discriminatory CANTAB tests. 37.6% of the variance in the severity of aMCI was predicted by OTS_PSFC, RVP_ A´, word list recognition scores, and education years. Psychosocial stressors (adverse childhood experiences, negative life events), subjective feelings of cognitive impairment, and RVP, the probability of false alarm, account for 40.0% of the DSOA score. Discussion: When MDD is ruled out, aMCI is linked to deficits in attention, executive functions, and memory. Psychosocial stressors did not have a statistically significant impact on aMCI or its severity. Enhanced false alarm response bias coupled with heightened psychological stress (including subjective perceptions of cognitive decline) may contribute to an increase in DSOA among older adults. Keyswords: depression, mild cognitive impairment, adverse childhood experiences, stress, anxiety
- Subjects
EXECUTIVE function; LIFE change events; STIMULUS &; response (Psychology); MILD cognitive impairment; ADVERSE childhood experiences
- Publication
Clinical Interventions in Aging, 2024, Vol 19, p1445
- ISSN
1178-1998
- Publication type
Article
- DOI
10.2147/CIA.S473730