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- Title
Sudden Hearing loss Associated with Mirtazapine Therapy: a Case Report.
- Authors
Dursun, Engin; Akpinar, Abdullah; Battal, Bilal
- Abstract
Mirtazapine is a tetracyclic piperazinoazepine analogue of mianserin and indicated for the treatment of major depressive disorder. It is a safe and well-tolerated drug for use in daily clinical practice. Mirtazapine has a relatively low incidence of side effects related with otorhinolaryngology. A 22-year-old male patient with major depression was prescribed mirtazapine. Within 24 hours after the first dosage the patient developed a sudden hearing loss and tinnitus without vertigo. Since there was neither concomitant medication use nor another medical illness, in addition to the absence of clinical, laboratory, and radiological evidence of a possible cause for sudden hearing loss and tinnitus, an association between mirtazapine and sudden hearing loss and tinnitus was suggested. In this report, we identify clinical and audiological characteristics of mirtazapine induced sudden hearing loss. Physicians should be aware of this possible adverse effect. Patients should be informed about the signs and symptoms of otological side effects and use of the drug should be discontinued at the first appearance of sudden hearing loss.
- Subjects
TREATMENT of deafness; MENTAL depression; THERAPEUTICS; PHYSICIAN practice patterns; OTOLARYNGOLOGY
- Publication
Klinik Psikofarmakoloji Bulteni, 2009, Vol 19, Issue 4, p417
- ISSN
1017-7833
- Publication type
Case Study