We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Nephrogenic fibrosing dermopathy.
- Authors
Ragunatha S; Palit A; Inamadar AC; Madraki RM; Yelikar BR; Ragunatha, S; Palit, Aparna; Inamadar, Arun C; Madraki, Ravindra M; Yelikar, B R
- Abstract
An adult female patient on hemodialysis for chronic renal failure presented with large, brownish, and indurated plaques with bound-down skin on both lower limbs and abdomen along with difficulty in movement of the legs. Histopathological features revealed thick collagen bundles admixed with mucin and intercalating spindle-like cells characteristic of nephrogenic fibrosing dermopathy (NFD). Immunohistochemical study showed prominent CD68 positivity and weak CD34 positivity suggesting that the plaques were more than 20-weeks old. NFD in patients with chronic renal failure of unknown cause is a poor prognostic indicator. Early detection before the development of contracture and prompt treatment of NFD and underlying renal failure may reverse this disabling condition.
- Publication
Indian Journal of Dermatology, Venereology & Leprology, 2009, Vol 75, Issue 1, p63
- ISSN
0378-6323
- Publication type
journal article