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- Title
Zur Detektion von Knochenmetastasen bei Patienten mit neuroendokrinen gastrointestinalen Tumoren.
- Authors
Steger, W.; Amthauer, H.; Vogl, T. J.; Wiedenmann, B.; Steger, S.; Eichstädt, H.
- Abstract
Introduction: In patients with neuroendocrine gastrointestinal tumors and liver metastases, but without known extrahepatic manifestations, liver transplantation may be indicated as curativ or „long-term-palliativ” therapy. For these patients the absence of bone lesions is mandatory. Methods: 4 patients with a histologically proven neuroendocrine tumor were examined in order to exclude further metastases. We compared the diagnostic value of somatostatin-receptor-scintigraphy (SRS), X-ray, 99mTc-DPD-scintigraphy, CT and MRI. Results: In all 4 patients bone metastases could be detected using SRS, CT und MRT. In one case MRI proved multiple infiltrations, while SRS showed only a solitary, focal lesion. 99mTc-DPD-scintigraphy was positive in 3 cases, X-ray in 1 case. Conclusion: As a diagnostic strategy we initially recommend somatostatin-receptor-scintigraphy. When locating suspect areas in SRS, MRI should be the method of choice for the exact evaluation of malignant bone infiltrations. A CT-guided biopsy is necessary to gain histological information.
- Publication
Der Radiologe, 1999, Vol 39, Issue 3, p235
- ISSN
0033-832X
- Publication type
Article
- DOI
10.1007/s001170050501