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- Title
Combination of two-dimensional shear wave elastography with ultrasound breast imaging reporting and data system in the diagnosis of breast lesions: a new method to increase the diagnostic performance.
- Authors
Li, Dan-Dan; Xu, Hui-Xiong; Guo, Le-Hang; Bo, Xiao-Wan; Li, Xiao-Long; Wu, Rong; Xu, Jun-Mei; Zhang, Yi-Feng; Zhang, Kun
- Abstract
<bold>Objectives: </bold>To evaluate the diagnostic performance of a new method of combined two-dimensional shear wave elastography (i.e. virtual touch imaging quantification, VTIQ) and ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) in the differential diagnosis of breast lesions.<bold>Materials and Methods: </bold>From September 2014 to December 2014, 276 patients with 296 pathologically proven breast lesions were enrolled in this study. The conventional US images were interpreted by two independent readers. The diagnosis performances of BI-RADS and combined BI-RADS and VTIQ were evaluated, including the area under the receiver operating characteristic curve (AUROC), sensitivity and specificity. Observer consistency was also evaluated.<bold>Results: </bold>Pathologically, 212 breast lesions were benign and 84 were malignant. Compared with BI-RADS alone, the AUROCs and specificities of the combined method for both readers increased significantly (AUROC: 0.862 vs. 0.693 in reader 1, 0.861 vs. 0.730 in reader 2; specificity: 91.5 % vs. 38.7 % in reader 1, 94.8 % vs. 47.2 % in reader 2; all P < .05). The Kappa value between the two readers for BI-RADS assessment was 0.614, and 0.796 for the combined method.<bold>Conclusion: </bold>The combined VTIQ and BI-RADS had a better diagnostic performance in the diagnosis of breast lesions in comparison with BI-RADS alone.<bold>Key Points: </bold>• Combination of conventional ultrasound and elastography distinguishes breast cancers more effectively. • Combination of conventional ultrasound and elastography increases observer consistency. • BI-RADS weights more than the 2D-SWE with an increase in malignancy probability.
- Subjects
BREAST cancer; ELASTOGRAPHY; BREAST imaging; ULTRASONIC imaging; IMAGING systems; BREAST; BREAST tumors; DIFFERENTIAL diagnosis; INFORMATION storage &; retrieval systems; MEDICAL databases; LONGITUDINAL method; PHARMACOKINETICS; MEDICAL radiology; RESEARCH evaluation; RECEIVER operating characteristic curves
- Publication
European Radiology, 2016, Vol 26, Issue 9, p3290
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-015-4163-8