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- Title
High-resolution imaging of the excised porcine heart at a whole-body 7 T MRI system using an 8Tx/16Rx pTx coil.
- Authors
Terekhov, Maxim; Elabyad, Ibrahim A.; Lohr, David; Hofmann, Ulrich; Schreiber, Laura M.
- Abstract
Introduction: MRI of excised hearts at ultra-high field strengths ( B 0 ≥7 T) can provide high-resolution, high-fidelity ground truth data for biomedical studies, imaging science, and artificial intelligence. In this study, we demonstrate the capabilities of a custom-built, multiple-element transceiver array customized for high-resolution imaging of excised hearts. Method: A dedicated 16-element transceiver loop array was implemented for operation in parallel transmit (pTx) mode (8Tx/16Rx) of a clinical whole-body 7 T MRI system. The initial adjustment of the array was performed using full-wave 3D-electromagnetic simulation with subsequent final fine-tuning on the bench. Results: We report the results of testing the implemented array in tissue-mimicking liquid phantoms and excised porcine hearts. The array demonstrated high efficiency of parallel transmits characteristics enabling efficient pTX-based B1+-shimming. Conclusion: The receive sensitivity and parallel imaging capability of the dedicated coil were superior to that of a commercial 1Tx/32Rx head coil in both SNR and T2*-mapping. The array was successfully tested to acquire ultra-high-resolution (0.1 × 0.1 × 0.8 mm voxel) images of post-infarction scar tissue. High-resolution (isotropic 1.6 mm3 voxel) diffusion tensor imaging-based tractography provided high-resolution information about normal myocardial fiber orientation.
- Subjects
MAGNETIC resonance imaging; DIFFUSION magnetic resonance imaging; CARDIAC imaging; HEART; SCARS; FIBER orientation; DIFFUSION tensor imaging; ARTIFICIAL intelligence
- Publication
MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine, 2023, Vol 36, Issue 2, p279
- ISSN
0968-5243
- Publication type
Article
- DOI
10.1007/s10334-023-01077-z