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- Title
Concurrent onset of acute lupus myocarditis, pulmonary arterial hypertension and digital gangrene in a lupus patient: a possible role of vasculitis to the rare disorders.
- Authors
Ando, Takayasu; Yamasaki, Yoshioki; Takakuwa, Yukiko; Iida, Harunobu; Asari, Yusa; Suzuki, Kanako; Uchida, Marina; Kotoku, Nozomi; Tanabe, Yasuhiro; Chosokabe, Motohiro; Takahashi, Masahide; Suzuki, Kengo; Akashi, Yoshihiro J.; Yamada, Hidehiro; Kawahata, Kimito
- Abstract
Acute lupus myocarditis and pulmonary arterial hypertension (PAH) are rare complications associated with systemic lupus erythematosus (SLE). No previous reports have shown the coexistence of these disorders. Here we present a 41-year-old patient with SLE who concurrently developed severe acute lupus myocarditis and PAH with digital gangrene as an initial manifestation. Acute lupus myocarditis and PAH were successfully treated with prednisolone and intravenous cyclophosphamide pulse therapy (600–700 mg × 6) along with anticoagulant therapy. Catheter-directed thrombolysis was required for digital gangrene caused by vasculitis. Concurrent development of these rare disorders may represent a common mechanism such vasculitis as an underlining cause of SLE.
- Subjects
PULMONARY hypertension; MYOCARDITIS; GANGRENE; PATIENTS; CYCLOPHOSPHAMIDE
- Publication
Modern Rheumatology Case Reports, 2020, Vol 4, Issue 1, p21
- ISSN
2472-5625
- Publication type
Article
- DOI
10.1080/24725625.2019.1650698