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- Title
右美托咪定治疗老年精神病患者无抽搐电休克的临床效果分析.
- Authors
张娜娜; 孔敏; 王成东; 刘昊昊; 童柱; 李斌; 武静茹
- Abstract
Objective: To investigate of the clinical effect of dexmedetomidine on the elderly mental illness patients without electroconvulsive therapy. Methods: 60 elderly mental illness patients who underwent with electroconvulsive therapy in our hospital from September 2015 to February 2019 were enrolled in this study. They were divided into divided into the dexmedetomidine group and control group accorded to the random number table method, 30 cases in each group. The two groups were given intravenous anesthesia with propofol, and the dexmedetomidine group was given a short bolus injection with dexmedetomidine 0.2µg/kg (20 mL) 10 min before electroconvulsive therapy, and the control group was bolused with 20 mL of normal saline. Record and compare the anesthetic effect of the two groups and the vital signs fluctuations. Results: The amount of propofol, recovery time and recovery time of the dexmedetomidine group were significantly lower or shorter than in the control group (P<0.05). The systolic blood pressure, diastolic blood pressure and heart rate of the two groups before anesthesia and without electroconvulsive shock for 20 min were within the normal range. There was no significant difference between the two groups (P>0.05). There were no significant differences in serum IgA and IgM between the two groups before and after treatment (P>0.05). The incidence of adverse reactions such as irritability, panic attacks, delayed recovery, headache, nausea and vomiting during the dexmedetomidine group were 6.7%, which was significantly lower than of the control group (36.7%, P<0.05). Conclusions: Dexmedetomidine for the treatment of elderly mental illness patients without convulsion electroconvulsive therapy will not have a negative impact on the vital signs and immune function of the body, can reduce the amount of propofol, improve the anesthetic effect, and have higher safety.
- Subjects
SHOCK therapy; MENTAL illness treatment; ELECTROCONVULSIVE therapy; SYSTOLIC blood pressure; POSTOPERATIVE nausea &; vomiting
- Publication
Progress in Modern Biomedicine, 2020, Vol 20, Issue 11, p1889
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2020.10.020