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- Title
帕金森病的临床治疗概况.
- Authors
李炜大; 汤占斌; 韩有泽; 霍鑫; 毕胜
- Abstract
Parkinson’s disease(PD), known medically as "primary paralysis paralysis," also known as "Parkinson’s disease," is a central nervous system degenerative disorder mainly caused by the presence of "substantia nigra " In dopamine(DA) neurons pathological changes after the reduction of dopamine synthesis, and its function antagonism of acetylcholine inhibition decreased, the excitement of acetylcholine relatively enhanced. The result of the imbalance between the two appeared "paralysis of paralysis". This review firstly summarizes the current clinical medicine for western medicine in the direction of the pathogenesis of PD(including levodopa, DA degrading enzyme inhibitors, DA receptor agonists, anticholinergic drugs), gene therapy targets, surgery(DBS) and physical therapy, and also introduces the treatment of traditional Chinese medicine and acupuncture and moxibustion treatment from the point of view of traditional Chinese medicine. PD has a serious impact on patients’ daily life and physical and mental health, we hope that through this review, we will provide broader clinical ideas and better solutions for PD comprehensive treatment.
- Publication
Progress in Modern Biomedicine, 2019, Vol 19, Issue 10, p1993
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2019.10.042