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- Title
Synthesis and Structure of 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides.
- Authors
Vasil'eva, O. S.; Gorodnicheva, N. V.; Makarenko, S. V.; Ostroglyadov, E. S.; Tyurenkov, I. N.; Perfilova, V. N.; Aleksandrova, S. M.
- Abstract
1-Alkoxycarbonylmethyl-4-heteryl-2-pyrrolidones were synthesized by alkylation of 4-heteryl-2-pyrrolidones. 2-(4-Heteryl-2-pyrrolidon-1-yl)acetamides were prepared through the reaction of N-esters with ammonia. The resulting acetamides of 2-pyrrolidones exhibit nootropic properties, antiarrhythmic and antiischemic activity.
- Subjects
ALKOXY compounds; CARBONYL compounds; PYRROLIDINONES; ALKYLATION; ACETAMIDE; AMMONIA; MYOCARDIAL depressants
- Publication
Russian Journal of General Chemistry, 2018, Vol 88, Issue 7, p1374
- ISSN
1070-3632
- Publication type
Article
- DOI
10.1134/S1070363218070046