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- Title
Effect of different types of dietary oils on growth performance and organ function in mice.
- Authors
Yingfang Zhou; Linyu Zhang; Xin Li; Sisi Yan; Ji Wang; Lixin Wen
- Abstract
This study aims to investigate the effects of lard, vegetables oils and their blend on the growth performance, liver, kidney and heart functions with specific objective to assess the potential health risks for specific human populations. In this study, mice were used as experimental model to simulate the dietary habits of specific human population. For this purpose, a total of 120 five-week old male C57BL/6J mice were randomly divided into eight groups. The experimental treatments were lard group 10% and lard group 15.5% (lard group based diet), RAO group 10% and RAO group 15% (rapeseed oil based diet), L-RAO 10 % and L-RAO 15% (lard and rapeseed oil blend based diet), OLO 10 % and OLO 15% (olive oil based diet). After 15 weeks, the blood, liver tissues, kidney tissues and heart tissues were collected to measure serum and tissues indexes. The results showed that the levels of serum triglyceride, cholesterol, high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were the lowest in the L-RAO 10 % and 15 % group. The ratio of HDL-C and LDL-C in the L-RAO 10% group was increased compared to other three groups with 10%. The serum alkaline phosphates level was markedly decreased in the L-RAO group compared to that of the lard 15.5% and RAO 15.5% groups. Compared with the lard group, the serum uric acid levels in the 10% ROA, L-ROA and OLO groups. Meanwhile, the serum lactate dehydrogenase (and αhydroxybutyrate dehydrogenase levels in the L-RAO group was lowest as compared to other treatments. This study demonstrated that the mixture of lard and rapeseed oil has the effect of reducing weight and 10% blended lard and rapeseed oil may have tendency to reduce the risk of coronary heart disease and gout in the body and have potential protective effect on the liver, kidney and heart.
- Subjects
HDL cholesterol; LDL cholesterol; OLIVE oil; VEGETABLE oils; RAPESEED oil
- Publication
Pakistan Journal of Agricultural Sciences, 2022, Vol 59, Issue 4, p717
- ISSN
0552-9034
- Publication type
Article
- DOI
10.21162/PAKJAS/22.135