We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Acalculous pyelonephritis and cholecystitis occurring simultaneously in a diabetic patient on sitagliptin therapy.
- Authors
Sahoo, Jayaprakash; Kamalanathan, Sadishkumar; Vivekanandan, Muthupillai; Palamalai Swaminathan, Rathinam
- Abstract
Dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of anti-diabetic drugs. They control both fasting and postprandial hyperglycemia by inhibiting degradation of incretin hormones, such as, glucagon-like peptide-1(GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Sitagliptin is the first DPP-4 inhibitor to be marketed in India. In addition to its glucose lowering effect, it also suppresses immunity resulting in various infections in a diabetes patient. Here, we describe the simultaneous development of two infections (acalculous pyelonephritis and cholecystitis) in a postmenopausal female patient, well-controlled on sitagliptin-based anti-diabetic therapy.
- Subjects
PYELONEPHRITIS treatment; CHOLECYSTITIS; PEOPLE with diabetes; SITAGLIPTIN; PHYSIOLOGICAL effects of glucose
- Publication
Journal of Pharmacology & Pharmacotherapeutics, 2015, Vol 6, Issue 3, p172
- ISSN
0976-500X
- Publication type
Article
- DOI
10.4103/0976-500X.162016