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- Title
Goat Milk Allergy and a Potential Role for Goat Milk in Cow's Milk Allergy.
- Authors
Benjamin-van Aalst, Olga; Dupont, Christophe; van der Zee, Lucie; Garssen, Johan; Knipping, Karen
- Abstract
In many parts of the world, goat milk has been part of the human diet for millennia. Allergy to goat's milk, not associated with allergy to cow's milk, is a rare disorder, although some cases have been described. Goat milk proteins have substantial homology with cow's milk proteins and even show cross-reactivity; therefore, they are not advised as an alternative to cow's milk for infants with IgE-mediated cow's milk allergies. However, there are indications that, due to the composition of the goat milk proteins, goat milk proteins show lower allergenicity than cow's milk due to a lower αS1-casein content. For this reason, goat milk might be a better choice over cow's milk as a first source of protein when breastfeeding is not possible or after the breastfeeding period. Additionally, some studies show that goat milk could play a role in specific types of non-IgE-mediated cow milk allergy or even in the prevention of sensitization to cow's milk proteins. This review discusses a possible role of goat milk in non-IgE mediated allergy and the prevention or oral tolerance induction of milk allergy.
- Subjects
BREASTFEEDING; RARE diseases; CATTLE; IMMUNOGLOBULINS; CASEINS; MILK proteins; MILK allergy; CYTOKINES; INTERLEUKINS
- Publication
Nutrients, 2024, Vol 16, Issue 15, p2402
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu16152402