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- Title
Mechanism of aortic balloon valvuloplasty: fracture of valvular calcific deposits.
- Authors
Isner, Jeffrey M.; Samuels, David A.; Slovenkai, Geralyn A.; Halaburka, Kimberly R.; Hougen, Thomas J.; Desnoyers, Mark R.; Fields, Constance D.; Salem, Deeb N.; Isner, J M; Samuels, D A; Slovenkai, G A; Halaburka, K R; Hougen, T J; Desnoyers, M R; Fields, C D; Salem, D N
- Abstract
Balloon valvuloplasty has been shown to acutely reduce the hemodynamic and symptomatic severity of calcific aortic stenosis. The mechanism by which this improvement is accomplished is not known. At necropsy, three patients who died after hemodynamically successful aortic balloon valvuloplasty were found to have aortic valve calcific deposits fractured at one or more sites. These findings suggest that fracture of leaflet calcium represents the basis for successful aortic balloon valvuloplasty.
- Subjects
PERCUTANEOUS balloon valvuloplasty; AORTIC stenosis; HEMODYNAMICS; AUTOPSY; AORTIC stenosis treatment; CATHETERIZATION; COMPARATIVE studies; RESEARCH methodology; MEDICAL cooperation; RESEARCH; EVALUATION research; CALCINOSIS
- Publication
Annals of Internal Medicine, 1988, Vol 108, Issue 3, p377
- ISSN
0003-4819
- Publication type
journal article
- DOI
10.7326/0003-4819-108-3-377