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- Title
EVALUAREA AFECTĂRII CUTANATE ÎN SCLEROZA SISTEMICĂ ŞI CORELAŢIILE ACESTEIA CU AFECTAREA VISCERALĂ.
- Authors
Groseanu, Laura; Daraban, Ana Maria; Bălănescu, Andra; Bojincă, Violeta; Predeţeanu, Denisa; Opriş, Daniela; Constantinescu, Cosmin; Berghea, Florian; Negru, Magda; Oprişan, Ioana; Ionescu, Ruxandra
- Abstract
Background: Systemic sclerosis (SSc) is a complex disease, skin thicness being the most obvious involvement. The "gold standard" method for the evaluation of dermal thickness is the modified Rodnan skin (mRSS). Many authors have reported correlations of this score with visceral involvement and prognosis. Objectives: To evaluate the correlation between mRSS and organ involvement in the two subset of SSc. Methods: Data from 55 SSc patients were collected during one year: demographics, visceral involvement according to MEDS evaluation sheet, lab tests. The mRSS was performed by 2 independent trained examiners. Statistical analysis was done with EpiInfo and SPSS 17.0 b Results: In the diffuse cutaneous group mean disease duration was 7. 8 years, mean mRSS was 17.5. We found a significant correlation of the mRSS with pulmonary fibrosis (p=0, 04), diastolic dysfunction (p=0, 03) and renal crisis (p=0, 00001). In the limited cutaneous group mean disease duration was 7. 23 years, mean mRSS was 8.2.. We found a signification correlation between mRSS and arrhythmias (p=0, 04). Conclusions: Although it is known that Rodnan skin score is a prognostic tool useful in the first 3 years of the disease we still found a significant correlation with pulmonary fibrosis, diastolic dysfunction and renal crisis in the diffuse SSc group and with arrhythmias in the limited SSc group even after several years of disease.
- Subjects
VISCERAL reflex; SKIN; SYSTEMIC scleroderma; ARRHYTHMIA; PULMONARY fibrosis; DIASTOLE (Cardiac cycle)
- Publication
Romanian Journal of Rheumatology / Revista Romana de Reumatologie, 2009, Vol 18, Issue 4, p248
- ISSN
1843-0791
- Publication type
Article