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- Title
Hypokalaemic paresis, hypertension, alkalosis and adrenal-dependent hyperadrenocorticism in a dog.
- Authors
Davies, D. R.; Foster, S. F.; Hopper, B. J.; Staudte, K. L.; O'Hara, A. J.; Irwin, P. J.
- Abstract
Generalised paresis, severe hypokalaemia and kaliuresis, metabolic alkalosis and hypertension, characteristic of mineralocorticoid excess, were identified in a dog with hyperadrenocorticism due to a functional adrenocortical carcinoma. Aldosterone concentration was decreased and deoxycorticosterone concentration increased in the presence of hypokalaemia. These metabolic abnormalities resolved with resection of the carcinoma. Mineralocorticoid excess in dogs with hyperadrenocorticism is generally considered to be of little clinical significance but resulted in the acute presentation of this patient. The possible pathogenesis of mineralocorticoid excess in this case of canine hyperadrenocorticism is discussed.
- Subjects
HYPERADRENOCORTICISM; DOG diseases; PARALYSIS; ALKALOSIS; MINERALOCORTICOIDS
- Publication
Australian Veterinary Journal, 2008, Vol 86, Issue 4, p139
- ISSN
0005-0423
- Publication type
Article
- DOI
10.1111/j.1751-0813.2008.00276.x