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- Title
Assessment of Mother-to-Child transmission of Hepatitis C Virus in Egyptian Pregnant Women.
- Authors
El-Sayed, Manal Hamdy; Elsayed Ebeid, Fatma Soliman; Kamal El-Din, Aya Mostafa; Mostafa, Rania Hassan; Abd El-Monem Mohammed, Belal Khaled
- Abstract
Background: The World Health Organization (WHO) has an ambitious plan to eliminate HCV by 2030. This new approach was fueled by increased appreciation of the global morbidity and mortality caused by hepatitis C, and the remarkable recent treatment developments. Objectives: To assess the mother-to-child transmission of hepatitis C virus in Egyptian pregnant women to inform on screening policies and strategy development. To measure prevelance of hepatitis C virus infection in pregnant women Methods: The current study was conducted to six thousand and seven hundred and thirty four (6734) women delivered in El Demerdash Maternity Hospital in the period from January 2018 till June 2018. Collection of detailed data from Patients files and divided them into non screened and screened by antibodies and who do PCR for HCV and data of their neonatal outcome Results: Comparison according to HCV PCR regarding labor characteristics show that cases with positive HCV PCR significantly had more frequent CS. Logistic regression for risk factors for HCV PCR among the studied cases show that only Previous hospitalization and previous transfusion were significant risk factors for positive HCV PCR. Conclusion: Previous hospitalization and previous transfusion were significant risk factors for positive HCV PCR. Pregnants with positive HCV PCR significantly had more lower hemoglobin than non-infected pregnant one and previous abortion and hospitalization may play a role in that.
- Subjects
WORLD Health Organization; HEPATITIS C virus; HEPATITIS C; PREGNANT women; VIRUS diseases; WOMEN'S hospitals; LABOR (Obstetrics)
- Publication
QJM: An International Journal of Medicine, 2021, Vol 114, pi287
- ISSN
1460-2725
- Publication type
Article
- DOI
10.1093/qjmed/hcab113.015