Found: 50
Select item for more details and to access through your institution.
Saccadic peak velocity and EEG as end-points for a serotonergic challenge test.
- Published in:
- Human Psychopharmacology: Clinical & Experimental, 2002, v. 17, n. 2, p. 83, doi. 10.1002/hup.374
- By:
- Publication type:
- Article
Estimation of plasma serotonin using isopycnic centrifugation.
- Published in:
- Human Psychopharmacology: Clinical & Experimental, 2000, v. 15, n. 6, p. 417, doi. 10.1002/1099-1077(200008)15:6<417::AID-HUP210>3.0.CO;2-W
- By:
- Publication type:
- Article
Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.
- Published in:
- Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02557-5
- By:
- Publication type:
- Article
Translatability of preclinical to early clinical tolerable and pharmacologically active dose ranges for central nervous system active drugs.
- Published in:
- Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02353-1
- By:
- Publication type:
- Article
Pseudocontinuous arterial spin labeling reveals dissociable effects of morphine and alcohol on regional cerebral blood flow.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2011, v. 31, n. 5, p. 1321, doi. 10.1038/jcbfm.2010.234
- By:
- Publication type:
- Article
Lessons Learned and Potentials for Improvement in CNS Drug Development: ISCTM Section on Designing the Right Series of Experiments.
- Published in:
- Innovations in Clinical Neuroscience, 2015, v. 12, p. 11S
- By:
- Publication type:
- Article
Diminished Posterior Precuneus Connectivity with the Default Mode Network Differentiates Normal Aging from Alzheimer's Disease.
- Published in:
- Frontiers in Aging Neuroscience, 2017, p. 1, doi. 10.3389/fnagi.2017.00097
- By:
- Publication type:
- Article
Orexin receptor antagonism: an ascending multiple-dose study with almorexant.
- Published in:
- Journal of Psychopharmacology, 2012, v. 26, n. 8, p. 1071, doi. 10.1177/0269881112448946
- By:
- Publication type:
- Article
Dopamine Modulates Reward System Activity During Subconscious Processing of Sexual Stimuli.
- Published in:
- Neuropsychopharmacology, 2012, v. 37, n. 7, p. 1729, doi. 10.1038/npp.2012.19
- By:
- Publication type:
- Article
Bioequivalence of subcutaneous injections of recombinant human follicle stimulating hormone (Puregon(R)) by Pen-injector and syringe.
- Published in:
- 1999
- By:
- Publication type:
- journal article
Reversal of mecamylamine‐induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses.
- Published in:
- British Journal of Clinical Pharmacology, 2018, v. 84, n. 5, p. 888, doi. 10.1111/bcp.13507
- By:
- Publication type:
- Article
Predicting CYP3A‐mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure.
- Published in:
- British Journal of Clinical Pharmacology, 2018, v. 84, n. 2, p. 358, doi. 10.1111/bcp.13459
- By:
- Publication type:
- Article
Pharmacological vs. classical approaches in the design of first in man clinical drug trials.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 12, p. 2807, doi. 10.1111/bcp.13422
- By:
- Publication type:
- Article
An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 8, p. 1676, doi. 10.1111/bcp.13268
- By:
- Publication type:
- Article
The use of a battery of pain models to detect analgesic properties of compounds: a two-part four-way crossover study.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 5, p. 976, doi. 10.1111/bcp.13183
- By:
- Publication type:
- Article
Pharmacokinetics and pharmacodynamics of a new highly concentrated intranasal midazolam formulation for conscious sedation.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 4, p. 721, doi. 10.1111/bcp.13163
- By:
- Publication type:
- Article
Model-based exposure-response analysis to quantify age related differences in the response to scopolamine in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2016, v. 82, n. 4, p. 1011, doi. 10.1111/bcp.13031
- By:
- Publication type:
- Article
Pharmacokinetic/pharmaco-dynamic modelling and simulation of the effects of different cannabinoid receptor type 1 antagonists on Δ<sup>9</sup>-tetrahydrocannabinol challenge tests.
- Published in:
- British Journal of Clinical Pharmacology, 2016, v. 81, n. 4, p. 713, doi. 10.1111/bcp.12852
- By:
- Publication type:
- Article
Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2013, v. 76, n. 6, p. 846, doi. 10.1111/bcp.12141
- By:
- Publication type:
- Article
Surinabant, a selective cannabinoid receptor type 1 antagonist, inhibits Δ<sup>9</sup>-tetrahydrocannabinol-induced central nervous system and heart rate effects in humans.
- Published in:
- British Journal of Clinical Pharmacology, 2013, v. 76, n. 1, p. 65, doi. 10.1111/bcp.12071
- By:
- Publication type:
- Article
Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men.
- Published in:
- British Journal of Clinical Pharmacology, 2013, v. 75, n. 6, p. 1455, doi. 10.1111/bcp.12015
- By:
- Publication type:
- Article
Pharmacokinetics and central nervous system effects of the novel dual NK<sub>1</sub>/NK<sub>3</sub> receptor antagonist GSK1144814 in alcohol-intoxicated volunteers.
- Published in:
- British Journal of Clinical Pharmacology, 2013, v. 75, n. 5, p. 1328, doi. 10.1111/bcp.12004
- By:
- Publication type:
- Article
Novel Δ<sup>9</sup>-tetrahydrocannabinol formulation Namisol® has beneficial pharmacokinetics and promising pharmacodynamic effects.
- Published in:
- British Journal of Clinical Pharmacology, 2012, v. 74, n. 1, p. 42, doi. 10.1111/j.1365-2125.2012.04164.x
- By:
- Publication type:
- Article
Central nervous system effects of the interaction between risperidone (single dose) and the 5-HT.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 6, p. 907, doi. 10.1111/j.1365-2125.2011.03902.x
- By:
- Publication type:
- Article
Pharmacokinetic-pharmacodynamic relationships of central nervous system effects of scopolamine in healthy subjects.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 6, p. 886, doi. 10.1111/j.1365-2125.2011.03936.x
- By:
- Publication type:
- Article
Functional biomarkers for the acute effects of alcohol on the central nervous system in healthy volunteers.
- Published in:
- British Journal of Clinical Pharmacology, 2011, v. 71, n. 3, p. 331, doi. 10.1111/j.1365-2125.2010.03846.x
- By:
- Publication type:
- Article
Central nervous system effects of alcohol at a pseudo-steady-state concentration using alcohol clamping in healthy volunteers.
- Published in:
- British Journal of Clinical Pharmacology, 2009, v. 68, n. 4, p. 524, doi. 10.1111/j.1365-2125.2009.03488.x
- By:
- Publication type:
- Article
Biomarkers for the effects of cannabis and THC in healthy volunteers.
- Published in:
- British Journal of Clinical Pharmacology, 2009, v. 67, n. 1, p. 5, doi. 10.1111/j.1365-2125.2008.03329.x
- By:
- Publication type:
- Article
A comparative study of two methods for attaining constant alcohol levels.
- Published in:
- British Journal of Clinical Pharmacology, 2008, v. 66, n. 5, p. 674, doi. 10.1111/j.1365-2125.2008.03268.x
- By:
- Publication type:
- Article
Central nervous system effects of moxonidine experimental sustained release formulation in patients with mild to moderate essential hypertension.
- Published in:
- British Journal of Clinical Pharmacology, 2003, v. 55, n. 6, p. 518, doi. 10.1046/j.1365-2125.2003.01796.x
- By:
- Publication type:
- Article
A study of the effects of long-term use on individual sensitivity to temazepam and lorazepam in a clinical population.
- Published in:
- British Journal of Clinical Pharmacology, 1997, v. 44, n. 3, p. 267, doi. 10.1046/j.1365-2125.1997.t01-1-00580.x
- By:
- Publication type:
- Article
Delta-9-Tetrahydrocannabinol-Induced Dopamine Release as a Function of Psychosis Risk: <sup>18</sup>F-Fallypride Positron Emission Tomography Study.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0070378
- By:
- Publication type:
- Article
Effects of Δ9-Tetrahydrocannabinol Administration on Human Encoding and Recall Memory Function: A Pharmacological fMRI Study.
- Published in:
- Journal of Cognitive Neuroscience, 2012, v. 24, n. 4, p. 588, doi. 10.1162/jocn_a_00156
- By:
- Publication type:
- Article
Effects of Δ9-Tetrahydrocannabinol Administration on Human Encoding and Recall Memory Function: A Pharmacological fMRI Study.
- Published in:
- Journal of Cognitive Neuroscience, 2012, v. 24, n. 3, p. 588, doi. 10.1162/jocn_a_00156
- By:
- Publication type:
- Article
Dopamine-Dependent Architecture of Cortico-Subcortical Network Connectivity.
- Published in:
- Cerebral Cortex, 2013, v. 23, n. 7, p. 1509, doi. 10.1093/cercor/bhs136
- By:
- Publication type:
- Article
Sensitivity of cognitive function tests to acute hypoxia in healthy subjects: a systematic literature review.
- Published in:
- Frontiers in Physiology, 2023, p. 1, doi. 10.3389/fphys.2023.1244279
- By:
- Publication type:
- Article
The effects of the nonselective benzodiazepine lorazepam and the α<sub>2</sub>/α<sub>3</sub> subunit-selective GABA<sub>A</sub> receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.
- Published in:
- Clinical Pharmacology in Drug Development, 2015, v. 4, n. 2, p. 149, doi. 10.1002/cpdd.134
- By:
- Publication type:
- Article
Δ9-Tetrahydrocannabinol Induces Dopamine Release in the Human Striatum.
- Published in:
- Neuropsychopharmacology, 2009, v. 34, n. 3, p. 759, doi. 10.1038/npp.2008.138
- By:
- Publication type:
- Article
PK/PD modeling of 5-hydroxytryptophan (5-HTP) challenge test with cortisol measurement in serum and saliva.
- Published in:
- Pharmacology Research & Perspectives, 2020, v. 8, n. 2, p. 1, doi. 10.1002/prp2.574
- By:
- Publication type:
- Article
Administration of oxathridine, a first‐in‐class histamine‐3 receptor partial agonist in healthy male volunteers: Central nervous system depression and pseudo‐hallucinations.
- Published in:
- British Journal of Clinical Pharmacology, 2024, v. 90, n. 1, p. 321, doi. 10.1111/bcp.15910
- By:
- Publication type:
- Article
Pharmacological profile of ALKS 7119, an investigational compound evaluated for the treatment of neuropsychiatric disorders, in healthy volunteers.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 6, p. 2909, doi. 10.1111/bcp.15229
- By:
- Publication type:
- Article
Biomarkers, designs, and interpretations of resting-state fMRI in translational pharmacological research: A review of state-of-the-Art, challenges, and opportunities for studying brain chemistry.
- Published in:
- Human Brain Mapping, 2017, v. 38, n. 4, p. 2276, doi. 10.1002/hbm.23516
- By:
- Publication type:
- Article
The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Pharmacological interactions between brivaracetam and ethanol in healthy males.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects.
- Published in:
- 2017
- By:
- Publication type:
- journal article
NS11821, a partial subtype-selective GABAA agonist, elicits selective effects on the central nervous system in randomized controlled trial with healthy subjects.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Reliability of System Identification Techniques to Assess Standing Balance in Healthy Elderly.
- Published in:
- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151012
- By:
- Publication type:
- Article
Concentration-effect relationships of two rilmenidine single-dose infusion rates in hypertensive patients<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2002, v. 72, n. 4, p. 419, doi. 10.1067/mcp.2002.127638
- By:
- Publication type:
- Article
The influence of cisapride and clarithromycin on QT intervals in healthy volunteers.
- Published in:
- Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 5, p. 542, doi. 10.1016/S0009-9236(98)90137-0
- By:
- Publication type:
- Article