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- Title
Dysanapsis as a Determinant of Lung Function in Development and Disease.
- Authors
McGinn, Elizabeth A.; Mandell, Erica W.; Smith, Bradford J.; Duke, Joseph W.; Bush, Andrew; Abman, Steven H.
- Abstract
The article discusses the concept of dysanapsis, which pertains to the disproportionate growth of airways and distal lung parenchyma, leading to discordant airway size compared to distal lung size. Topics include the historical development of dysanapsis concept; its relevance in healthy individuals and its role as a risk factor in the development and progression of lung diseases across the lifespan; and bronchopulmonary dysplasia (BPD), asthma and chronic obstructive pulmonary disease (COPD).
- Publication
American Journal of Respiratory & Critical Care Medicine, 2023, Vol 208, Issue 9, p956
- ISSN
1073-449X
- Publication type
Article
- DOI
10.1164/rccm.202306-1120PP