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- Title
Maternal haemodynamic effects of oxytocin bolus or infusion in the third stage of labour.
- Authors
Fatemeh, Foroozanfard; Zohreh, Sadat; Abbas, Mousavi Gholam; Layla, Hatami
- Abstract
Objectives: The safety of bolus oxytocin has been questioned due to reports of maternal hemodynamic consequences. This study compared maternal haemodynamic effects of oxytocin bolus or infusion in the third stage of vaginal delivery. Methodology: This was a randomized double-blind clinical trial in 170 women who received (10IU) intravenous oxytocin bolus or infusion in third stage of labour. Mean arterial pressure (MAP) and heart rate (HR) were measured before delivery and 1, 5, 10, 20 minutes after administration of oxytocin. These serial measurements and postpartum outcome were compared in two groups. Results were analyzed using analysis of variance for repeated measures, t-test, Man U Whitney, Fisher exact test, and chi-square test. Results: Findings showed MAP and HR did not vary between two groups (p= 0.38 and p= 0.65 respectively. Length of the third stage of labour, retained placenta and reduction in haemoglobin concentration for the bolus group was less than infusion group (p=0.000, p=0.042 and P=0.036 respectively). Other postpartum outcomewas similar in two groups. Conclusion: Bolus oxytocin is not associated with adverse maternal hemodynamics and appeared to beas effective and can safely be administered in the third stage of labour.
- Subjects
HEMODYNAMICS; OXYTOCIN; HEART beat; DELIVERY (Obstetrics); LABOR (Obstetrics); UTERINE contraction
- Publication
Pakistan Journal of Medical Sciences, 2011, Vol 27, Issue 3, p656
- ISSN
1682-024X
- Publication type
Article