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- Title
Intraosseous pressure measurement during iliac bone marrow biopsy: its feasibility and difference of IOP in diseased marrow and non-diseased marrow.
- Authors
Vicentini, Joao Rafael T.; Habibollahi, Sina; Habib, Ukasha; Chang, Connie Y.
- Abstract
Objective: The purposes of this study were (1) to establish the feasibility and safety of an imaging-guided technique for intraosseous pressure (IOP) measurement in a large cohort of patients, and (2) to compare IOP values between normal and diseased bone marrow. Methods: Adult patients undergoing CT-guided marrow biopsy were prospectively and consecutively enrolled from November 2020 to February 2022. IOP measurements were obtained connecting the biopsy needle to a monitoring device using a standard arterial line setup. Clinical data including sex, age and pathology results were obtained. Student t test and Pearson correlation were used for continuous variables comparisons. Univariable analyses were performed using Fisher's exact test. A P value of.05 was considered statistically significant. Results: A total of 139 participants were initially enrolled, and four were excluded during technique optimization. There were no complications related to the measurement technique. Ninety participants (90/135, 67%) had histology confirming marrow pathology. The participants in the diseased marrow group were older than those in the normal marrow group (63 ± 14 vs. 55 ± 14 years; P <.01). There was no difference in mean IOP between both groups (66 ± 23 vs. 64 ± 28 mmHg; P =.69). There was no correlation between mean arterial blood pressure and mean IOP (P =.08). Conclusion: There was no difference in IOP measurements between patients with normal and diseased marrow undergoing CT-guided biopsy. IOP does not appear to be influenced by systemic blood pressure. No complication occurred during the procedures.
- Subjects
BONE marrow examination; BONE marrow; PRESSURE measurement; NEEDLE biopsy; PEARSON correlation (Statistics); FISHER exact test
- Publication
Skeletal Radiology, 2024, Vol 53, Issue 3, p481
- ISSN
0364-2348
- Publication type
Article
- DOI
10.1007/s00256-023-04431-3